Pyruvate Carboxylase-IN-1

Modify Date: 2024-01-12 20:45:01

Pyruvate Carboxylase-IN-1 structure	Common Name	Pyruvate Carboxylase-IN-1
	CAS Number	70205-50-4	Molecular Weight	242.27
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₅H₁₄O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Pyruvate Carboxylase-IN-1

Pyruvate Carboxylase-IN-1 (compound 37) is a potent inhibitor of pyruvate carboxylase (PC) with IC50s of 0.204 and 0.104 μM in cell lysate-based and cell-based PC activity, respectively. Pyruvate Carboxylase-IN-1 is a natural analog of erianin. Pyruvate Carboxylase-IN-1 inhibites the enzymatic activity of PC, mediating the anticancer effect in human hepatocellular carcinoma (HCC)[1].

Name	Pyruvate Carboxylase-IN-1

Description	Pyruvate Carboxylase-IN-1 (compound 37) is a potent inhibitor of pyruvate carboxylase (PC) with IC50s of 0.204 and 0.104 μM in cell lysate-based and cell-based PC activity, respectively. Pyruvate Carboxylase-IN-1 is a natural analog of erianin. Pyruvate Carboxylase-IN-1 inhibites the enzymatic activity of PC, mediating the anticancer effect in human hepatocellular carcinoma (HCC)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Sheng Y, et al. Identification of Pyruvate Carboxylase as the Cellular Target of Natural Bibenzyls with Potent Anticancer Activity against Hepatocellular Carcinoma via Metabolic Reprogramming. J Med Chem. 2022;65(1):460-484.

Molecular Formula	C₁₅H₁₄O₃
Molecular Weight	242.27

DC Chemicals Limited
China
Product Name: Pyruvate Carboxylase-IN-1
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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