Nargenicin A1

Modify Date: 2024-01-01 19:05:06

Nargenicin A1 structure	Common Name	Nargenicin A1
	CAS Number	70695-02-2	Molecular Weight	515.60
	Density	1.31g/cm3	Boiling Point	718.3ºC at 760 mmHg
	Molecular Formula	C₂₈H₃₇NO₈	Melting Point	N/A
	MSDS	N/A	Flash Point	388.2ºC

Use of Nargenicin A1

Nargenicin A1 is an antibiotic agent against various Gram-positive bacteria. Nargenicin A1 shows anti-inflammatory activity. Nargenicin A1 protects HINAE cells against Tacrolimus (HY-13756)-induced DNA damage and apoptosis. Nargenicin A1 can also be used for the research of acute myeloid leukemia[1].

Name	nargenicin a,

Description	Nargenicin A1 is an antibiotic agent against various Gram-positive bacteria. Nargenicin A1 shows anti-inflammatory activity. Nargenicin A1 protects HINAE cells against Tacrolimus (HY-13756)-induced DNA damage and apoptosis. Nargenicin A1 can also be used for the research of acute myeloid leukemia[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Research Areas >> Infection Research Areas >> Inflammation/Immunology Signaling Pathways >> Anti-infection >> Bacterial
References	[1]. Da Hye Kwon, et al. Nargenicin A1 attenuates lipopolysaccharide-induced inflammatory and oxidative response by blocking the NF-κB signaling pathway. EXCLI J. 2021 May 28;20:968-982. [2]. Dhakal D, et al. Characterization of Tailoring Steps of Nargenicin A1 Biosynthesis Reveals a Novel Analogue with Anticancer Activities. ACS Chem Biol. 2020 Jun 19;15(6):1370-1380.

Description

Related Catalog

Signaling Pathways >> Apoptosis >> Apoptosis

Research Areas >> Cancer

Research Areas >> Infection

Research Areas >> Inflammation/Immunology

Signaling Pathways >> Anti-infection >> Bacterial

References

[1]. Da Hye Kwon, et al. Nargenicin A1 attenuates lipopolysaccharide-induced inflammatory and oxidative response by blocking the NF-κB signaling pathway. EXCLI J. 2021 May 28;20:968-982.

[2]. Dhakal D, et al. Characterization of Tailoring Steps of Nargenicin A1 Biosynthesis Reveals a Novel Analogue with Anticancer Activities. ACS Chem Biol. 2020 Jun 19;15(6):1370-1380.

Density	1.31g/cm3
Boiling Point	718.3ºC at 760 mmHg
Molecular Formula	C₂₈H₃₇NO₈
Molecular Weight	515.60
Flash Point	388.2ºC
Exact Mass	515.25200
PSA	127.31000
LogP	2.40040
Index of Refraction	1.595

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: U-59760
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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