Isoamyl 4-Methoxycinnamate

Modify Date: 2024-01-04 11:50:30

Isoamyl 4-Methoxycinnamate Structure
Isoamyl 4-Methoxycinnamate structure
Common Name Isoamyl 4-Methoxycinnamate
CAS Number 71617-10-2 Molecular Weight 248.318
Density 1.0±0.1 g/cm3 Boiling Point 362.8±17.0 °C at 760 mmHg
Molecular Formula C15H20O3 Melting Point N/A
MSDS Chinese USA Flash Point 151.6±15.5 °C

 Use of Isoamyl 4-Methoxycinnamate


Amiloxate is a UV-filter with anti-inflammatory activity[1].

 Names

Name Isoamyl 4-Methoxycinnamate
Synonym More Synonyms

 Isoamyl 4-Methoxycinnamate Biological Activity

Description Amiloxate is a UV-filter with anti-inflammatory activity[1].
Related Catalog
In Vitro Amiloxate (isoamyl p-methoxycinnamate, 10% w/w) shows anti-inflammatory effect by inhibiting the edema (83%)[1].
References

[1]. Céline Couteau, et al. UV Filters, Ingredients with a Recognized Anti-Inflammatory Effect. PLoS One. 2012; 7(12): e46187.

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 362.8±17.0 °C at 760 mmHg
Molecular Formula C15H20O3
Molecular Weight 248.318
Flash Point 151.6±15.5 °C
Exact Mass 248.141251
PSA 35.53000
LogP 4.06
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.524

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UD3393500
CHEMICAL NAME :
2-Propenoic acid, 3-(4-methoxyphenyl)-, 3-methylbutyl ester
CAS REGISTRY NUMBER :
71617-10-2
BEILSTEIN REFERENCE NO. :
3132627
LAST UPDATED :
199612
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C15-H20-O3
MOLECULAR WEIGHT :
248.35

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
9600 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 30,803,1992
TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>20 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 30,803,1992 ** REPRODUCTIVE DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
22500 mg/kg
SEX/DURATION :
female 6-15 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Effects on Embryo or Fetus - fetal death
REFERENCE :
FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 30,803,1992

 Safety Information

Hazard Statements H413
Hazard Codes Xi
RIDADR NONH for all modes of transport
WGK Germany 2.0
RTECS UD3393500
HS Code 2918990090

 Synthetic Route

~90%

Isoamyl 4-Methoxycinnamate Structure

Isoamyl 4-Metho...

CAS#:71617-10-2

Literature: List, Benjamin; Doehring, Arno; Hechavarria Fonseca, Maria T.; Job, Andreas; Rios Torres, Ramon Tetrahedron, 2006 , vol. 62, # 2-3 p. 476 - 482

~%

Isoamyl 4-Methoxycinnamate Structure

Isoamyl 4-Metho...

CAS#:71617-10-2

Literature: Journal of the American Chemical Society, , vol. 70, p. 1982

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Isoamyl 4-Methoxycinnamate Structure

Isoamyl 4-Metho...

CAS#:71617-10-2

Literature: Tetrahedron, , vol. 62, # 2-3 p. 476 - 482

 Customs

HS Code 2918990090
Summary 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Articles3

More Articles
[Analysis of the volatile oils chemical constituents of roots of Actinidia deliciosa].

Zhong Yao Cai 31(5) , 677-8, (2008)

To analyze the volatile oils chemical constituents of roots of Actinidia deliciosa.The volatile oils fraction of roots of Actinidia deliciosa. were extracted by water vapor distilling, and then the co...

Embryotoxicity study of propenoic acid, 3-(4-methoxyphenyl)-3-methylbutylester in the Wistar rat.

Food Chem. Toxicol. 30(9) , 803-7, (1992)

3-(4-methoxyphenyl)-3-methylbutylester, propenoic acid (MPMBE; CAS no. 71617-10-2), a UVB-light filter used for sun protection of the skin, was administered once daily by intragastric gavage to pregna...

Photo-allergic contact dermatitis caused by isoamyl p-methoxycinnamate in an 'organic' sunscreen.

Contact Dermatitis 64(2) , 115-6, (2011)

 Synonyms

3-(4-methoxyphenyl)-2-propenoic acid 3-methylbutyl ester
Neo Heliopan
isoamyl p-methoxycinnamate
3-Methylbutyl (2E)-3-(4-methoxyphenyl)acrylate
amiloxate
Isoamyl 4-methoxycinnamate
Isopentyl 4-methoxycinnamate
2-Propenoic acid, 3-(4-methoxyphenyl)-, 3-methylbutyl ester
isopentyl p-methoxycinnamate
2-Propenoic acid, 3-(4-methoxyphenyl)-, 3-methylbutyl ester, (2E)-
3-Methylbutyl 3-(4-methoxyphenyl)-2-propenoate
ISOPENTYL-4-METHOXYCINNAMATE
EINECS 275-702-5
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