Aflatoxin B2

Modify Date: 2024-01-03 13:24:20

Aflatoxin B2 Structure
Aflatoxin B2 structure
 Common Name Aflatoxin B2
CAS Number 7220-81-7 Molecular Weight 314.289
Density 1.52±0.1 g/cm3 Boiling Point 521.0±50.0 °C at 760 mmHg
Molecular Formula C17H14O6 Melting Point 305 ºC (分解) (chloroform )
MSDS Chinese USA Flash Point 234.0±30.2 °C
Symbol GHS06 GHS08
GHS06, GHS08		 Signal Word Danger

 Use of Aflatoxin B2


Aflatoxin B2 is a major naturally produced aflatoxin. Aflatoxin B2 is a mycotoxin produced by the fungi Aspergillus flavus and Aspergillus parasiticus.The level of toxicity associated with Aflatoxin is Aflatoxin B1>Aflatoxin M1>Aflatoxin G1>Aflatoxin B2>Aflatoxin M2>Aflatoxin G2[1].

 Names

Name Aflatoxin B2
Synonym More Synonyms

 Aflatoxin B2 Biological Activity

Description Aflatoxin B2 is a major naturally produced aflatoxin. Aflatoxin B2 is a mycotoxin produced by the fungi Aspergillus flavus and Aspergillus parasiticus.The level of toxicity associated with Aflatoxin is Aflatoxin B1>Aflatoxin M1>Aflatoxin G1>Aflatoxin B2>Aflatoxin M2>Aflatoxin G2[1].
Related Catalog
References

[1]. Kumar P, et al. Aflatoxins: A Global Concern for Food Safety, Human Health and Their Management. Front Microbiol. 2017 Jan 17;7:2170.

 Chemical & Physical Properties

Density 1.52±0.1 g/cm3
Boiling Point 521.0±50.0 °C at 760 mmHg
Melting Point 305 ºC (分解) (chloroform )
Molecular Formula C17H14O6
Molecular Weight 314.289
Flash Point 234.0±30.2 °C
Exact Mass 314.079041
PSA 74.97000
LogP 0.37
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.660
Water Solubility Practically insoluble (0.012 g/L) (25 ºC)

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
GY1722000
CAS REGISTRY NUMBER :
7220-81-7
BEILSTEIN REFERENCE NO. :
1355115
LAST UPDATED :
199612
DATA ITEMS CITED :
28
MOLECULAR FORMULA :
C17-H14-O6
MOLECULAR WEIGHT :
314.31
WISWESSER LINE NOTATION :
T F5 C6 B655 DOV GV OO QOT&&TTJ LO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - duck
DOSE/DURATION :
1700 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Bird - duck
DOSE/DURATION :
1680 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
600 mg/kg/8W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors
TYPE OF TEST :
DNA adduct
TYPE OF TEST :
DNA adduct

MUTATION DATA

TYPE OF TEST :
DNA adduct
TEST SYSTEM :
Mammal - species unspecified Lymphocyte
DOSE/DURATION :
50 umol/L
REFERENCE :
CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 3,423,1982 *** REVIEWS *** IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 1,145,1972 IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 10,51,1976 IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 56,245,1993 TOXICOLOGY REVIEW LLOYA2 Lloydia. (Cincinnati, OH) V.1-41, 1938-78. For publisher information, see JNPRDF. Volume(issue)/page/year: 38,21,1975 TOXICOLOGY REVIEW BAREA8 Bacteriological Reviews. (Washington, DC) V.1-41, 1937-77. Volume(issue)/page/year: 30,460,1966 TOXICOLOGY REVIEW PMDCAY Progress in Medical Chemistry. (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.1- 1961- Volume(issue)/page/year: 10,85,1974 TOXICOLOGY REVIEW IJNDAN Indian Journal of Nutrition and Dietetics. (Sri Avinashilingam Home Science College for Women, Coimbatore 641 043, India) V.7- 1970- Volume(issue)/page/year: 8,85,1971

 Safety Information

Symbol GHS06 GHS08
GHS06, GHS08
Signal Word Danger
Hazard Statements H300 + H310 + H330-H350
Precautionary Statements P201-P260-P264-P280-P284-P301 + P310
Personal Protective Equipment Eyeshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes T+: Very toxic;
Risk Phrases R45
Safety Phrases S36;S45;S53
RIDADR UN 3462 6
WGK Germany 3
RTECS GY1722000
Packaging Group I
Hazard Class 6.1(a)
HS Code 29322090

 Articles28

More Articles
Development and validation of an UHPLC-MS/MS method for the determination of mycotoxins in grass silages.

Food Addit. Contam. Part A. Chem. Anal. Control. Expo. Risk Assess. 32 , 2101-12, (2015)

An ultra-high-performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) multi-mycotoxin analytical method was developed to simultaneously identify and quantify 20 mycotoxins in grass si...

A multi-analyte LC-MS/MS method for the analysis of 23 mycotoxins in different sorghum varieties: the forgotten sample matrix.

Food Chem. 177 , 397-404, (2015)

An LC-MS/MS method was developed and validated for the detection and quantification of 23 mycotoxins in different varieties of sorghum. The method performance characteristics were as follows: suitable...

Stability of aflatoxins in solution.

J. AOAC Int. 95(4) , 1084-8, (2012)

The stability of aflatoxins B1, B2, G1, and G2 was studied in solutions containing different concentrations of water, acetonitrile, and/or methanol, and in autosampler vials treated with nitric acid o...

 Synonyms

(6aR,9aS)-4-Methoxy-2,3,6a,8,9,9a-hexahydrocyclopenta[c]furo[3',2':4,5]furo[2,3-h]chromene-1,11-dione
EINECS 230-618-8
Aflatoxin B2
(6aR-cis)-2,3,6a,8,9,9a-hexahydro-4-methoxy-cyclopenta[c]furo[3',2',4,5]furo[2,3-h][1]benzopyran-1,11-dione
Aflatoxin-B(2)
Dihydroaflatoxine B1
Cyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione, 2,3,6a,8,9,9a-hexahydro-4-methoxy-, (6aR,9aS)-
Dihydroaflatoxin B1
Aflatoxin B2 solution
MFCD00078140
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Related Compounds: More...
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1052616-31-5
C21H22ClN3O6
1014023-77-8
(E)-1-(2-cyano-3-oxo-3-(phenethylamino)prop-1-en-1-yl)piperidine-4-carboxylic acid
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4-(4-Hydroxyanilino)-6-(2,5-dichloroanilino)pyrimidine
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Chemsrc provides Aflatoxin B2(CAS#:7220-81-7) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Aflatoxin B2 are included as well.>> amp version: Aflatoxin B2

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