AFLATOXIN B1

Modify Date: 2024-01-02 18:10:03

AFLATOXIN B1 Structure
AFLATOXIN B1 structure
 Common Name AFLATOXIN B1
CAS Number 1162-65-8 Molecular Weight 312.274
Density 1.6±0.1 g/cm3 Boiling Point 528.2±50.0 °C at 760 mmHg
Molecular Formula C17H12O6 Melting Point 268-269 °C
MSDS Chinese USA Flash Point 237.7±30.2 °C
Symbol GHS06 GHS08
GHS06, GHS08		 Signal Word Danger
Purity Quantity Budget Inquiry

 Use of AFLATOXIN B1


Aflatoxin B1 (AFB1) is a Class 1A carcinogen, which is a secondary metabolite of Aspergillus flavus and A. parasiticus. Aflatoxin B1 (AFB1) mainly induces the transversion of G-->T in the third position of codon 249 of the p53 tumor suppressor gene, resulting in mutation[1][2].

 Names

Name aflatoxin B1
Synonym More Synonyms

 AFLATOXIN B1 Biological Activity

Description Aflatoxin B1 (AFB1) is a Class 1A carcinogen, which is a secondary metabolite of Aspergillus flavus and A. parasiticus. Aflatoxin B1 (AFB1) mainly induces the transversion of G-->T in the third position of codon 249 of the p53 tumor suppressor gene, resulting in mutation[1][2].
Related Catalog
Target

Human Endogenous Metabolite

References

[1]. Gizachew D, et al. Aflatoxin B1 (AFB1) production by Aspergillus flavus and Aspergillus parasiticus on ground Nyjer seeds: The effect of water activity and temperature. Int J Food Microbiol. 2019 May 2;296:8-13.

[2]. Aguilar F, et al. Aflatoxin B1 induces the transversion of G-->T in codon 249 of the p53 tumor suppressor gene in human hepatocytes. Proc Natl Acad Sci U S A. 1993 Sep 15;90(18):8586-90.

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Boiling Point 528.2±50.0 °C at 760 mmHg
Melting Point 268-269 °C
Molecular Formula C17H12O6
Molecular Weight 312.274
Flash Point 237.7±30.2 °C
Exact Mass 312.063385
PSA 74.97000
LogP 0.45
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.687

 Safety Information

Symbol GHS06 GHS08
GHS06, GHS08
Signal Word Danger
Hazard Statements H300 + H310 + H330-H350
Precautionary Statements P201-P260-P264-P280-P284-P301 + P310
Personal Protective Equipment Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes T+,T,Xn,F
Risk Phrases 45-46-26/27/28-36-20/21/22-11-65-48/23/24/25-36/38-39/23/24/25-23/24/25
Safety Phrases 53-45-36-26-16-24-7
RIDADR UN 3462 6.1/PG 1
WGK Germany 3
RTECS GY1925000
Packaging Group I

 Articles123

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Aflatoxins contamination in Pakistani brown rice: a comparison of TLC, HPLC, LC-MS/MS and ELISA techniques.

Toxicol. Mech. Methods 24(8) , 544-51, (2014)

Advancement in the field of analytical food-chemistry has explored various experimental techniques for aflatoxins (AFs) quantification. The present study was aimed to compare four different techniques...

Deoxynivalenol-mimic nanobody isolated from a naïve phage display nanobody library and its application in immunoassay.

Anal. Chim. Acta 887 , 201-8, (2015)

In this study, using mycotoxin deoxynivalenol (DON) as a model hapten, we developed a nanobody-based environmental friendly immunoassay for sensitive detection of DON. Two nanobodies (N-28 and N-31) w...

 Synonyms

Cyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione, 2,3,6a,9a-tetrahydro-4-methoxy-, (6aR,9aS)-
Aflatoxin B1
Aflatoxin B1 Crystalline
(-)-Aflatoxin B1
(6aR,9aS)-4-Methoxy-2,3,6a,9a-tetrahydrocyclopenta[c]furo[3',2':4,5]furo[2,3-h]chromene-1,11-dione
Aflatoxin B1, crystalline
MFCD00869647
Aflatoxin
EINECS 214-603-3
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Chemsrc provides AFLATOXIN B1(CAS#:1162-65-8) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of AFLATOXIN B1 are included as well.>> amp version: AFLATOXIN B1

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