Bromo-PEG6-bromide

Modify Date: 2024-01-10 03:32:50

Bromo-PEG6-bromide Structure
Bromo-PEG6-bromide structure
Common Name Bromo-PEG6-bromide
CAS Number 72713-23-6 Molecular Weight 452.18
Density N/A Boiling Point N/A
Molecular Formula C14H28Br2O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Bromo-PEG6-bromide


Bromo-PEG6-bromide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

 Names

Name Br-PEG6-bromide
Synonym More Synonyms

 Bromo-PEG6-bromide Biological Activity

Description Bromo-PEG6-bromide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2].
References

[1]. Mulyana Y, et al. Oligonuclear polypyridylruthenium(II) complexes incorporating flexible polar and non-polar bridges: synthesis, DNA-binding and cytotoxicity. Dalton Trans. 2011 Feb 21;40(7):1510-23.

[2]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Molecular Formula C14H28Br2O6
Molecular Weight 452.18

 Synonyms

MFCD30536166