Benzyl-PEG6-bromide

Modify Date: 2024-04-07 16:13:06

Benzyl-PEG6-bromide Structure
Benzyl-PEG6-bromide structure
Common Name Benzyl-PEG6-bromide
CAS Number 1449202-44-1 Molecular Weight 435.35
Density 1.225±0.06 g/cm3(Predicted) Boiling Point 481.4±40.0 °C(Predicted)
Molecular Formula C19H31BrO6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Benzyl-PEG6-bromide


Benzyl-PEG6-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Benzyl-PEG6-bromide

 Benzyl-PEG6-bromide Biological Activity

Description Benzyl-PEG6-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.225±0.06 g/cm3(Predicted)
Boiling Point 481.4±40.0 °C(Predicted)
Molecular Formula C19H31BrO6
Molecular Weight 435.35