5-Chloro-2-pyrazinemethanol

Modify Date: 2024-01-09 15:34:13

5-Chloro-2-pyrazinemethanol Structure
5-Chloro-2-pyrazinemethanol structure
Common Name 5-Chloro-2-pyrazinemethanol
CAS Number 72788-94-4 Molecular Weight 144.559
Density 1.422±0.06 g/cm3 Boiling Point 255.7±35.0 °C at 760 mmHg
Molecular Formula C5H5ClN2O Melting Point 62-63 ºC
MSDS N/A Flash Point 108.5±25.9 °C

 Names

Name (5-Chloropyrazin-2-yl)methanol
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.422±0.06 g/cm3
Boiling Point 255.7±35.0 °C at 760 mmHg
Melting Point 62-63 ºC
Molecular Formula C5H5ClN2O
Molecular Weight 144.559
Flash Point 108.5±25.9 °C
Exact Mass 144.009033
PSA 46.01000
LogP -0.54
Vapour Pressure 0.0±0.5 mmHg at 25°C
Index of Refraction 1.579
Storage condition 2-8°C

 Safety Information

Hazard Codes Xi
HS Code 2933990090

 Synthetic Route

~50%

5-Chloro-2-pyrazinemethanol Structure

5-Chloro-2-pyra...

CAS#:72788-94-4

Literature: IRONWOOD PHARMACEUTICALS, INC.; HUDSON, Colleen; BARDEN, Timothy, C.; JIA, James; MERMERIAN, Ara; PENG, Bo; YANG, Jane; YU, Xiang, Y.; SPROTT, Kevin Patent: WO2012/88469 A1, 2012 ; Location in patent: Page/Page column 151-152 ; WO 2012/088469 A1

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5-Chloro-2-pyrazinemethanol Structure

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CAS#:72788-94-4

Literature: WO2009/134668 A2, ; Page/Page column 29; 30 ; WO 2009/134668 A2

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5-Chloro-2-pyrazinemethanol Structure

5-Chloro-2-pyra...

CAS#:72788-94-4

Literature: Kmentova, Iveta; Sutherland, Hamish S.; Palmer, Brian D.; Blaser, Adrian; Franzblau, Scott G.; Wan, Baojie; Wang, Yuehong; Ma, Zhenkun; Denny, William A.; Thompson, Andrew M. Journal of Medicinal Chemistry, 2010 , vol. 53, # 23 p. 8421 - 8439

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5-Chloro-2-pyrazinemethanol Structure

5-Chloro-2-pyra...

CAS#:72788-94-4

Literature: WO2011/14774 A1, ; Page/Page column 23 ;

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5-Chloro-2-pyrazinemethanol Structure

5-Chloro-2-pyra...

CAS#:72788-94-4

Literature: WO2012/88469 A1, ; WO 2012/088469 A1

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

(5-Chloro-2-pyrazinyl)methanol
2-Pyrazinemethanol, 5-chloro-
(5-Chloropyrazin-2-yl)methanol
5-Chloro-2-pyrazinemethanol
2-Chloro-5-(hydroxymethyl)pyrazine