2-Chloropropane

Modify Date: 2024-01-02 11:37:30

2-Chloropropane Structure
2-Chloropropane structure
Common Name 2-Chloropropane
CAS Number 75-29-6 Molecular Weight 78.541
Density 0.9±0.1 g/cm3 Boiling Point 37.3±8.0 °C at 760 mmHg
Molecular Formula C3H7Cl Melting Point -118 °C
MSDS Chinese USA Flash Point -35.0±0.0 °C
Symbol GHS02 GHS05 GHS07
GHS02, GHS05, GHS07
Signal Word Danger

 Names

Name 2-Chloropropane
Synonym More Synonyms

 Chemical & Physical Properties

Density 0.9±0.1 g/cm3
Boiling Point 37.3±8.0 °C at 760 mmHg
Melting Point -118 °C
Molecular Formula C3H7Cl
Molecular Weight 78.541
Flash Point -35.0±0.0 °C
Exact Mass 78.023628
LogP 1.85
Vapour Pressure 488.8±0.1 mmHg at 25°C
Index of Refraction 1.379
Stability Stable. Incompatible with strong oxidizing agents, strong bases. Highly flammable - note low flash point. Cool to zero C before opening.
Water Solubility 3.1 g/L (20 ºC)

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TX4410000
CHEMICAL NAME :
Propane, 2-chloro-
CAS REGISTRY NUMBER :
75-29-6
BEILSTEIN REFERENCE NO. :
1730782
LAST UPDATED :
199710
DATA ITEMS CITED :
12
MOLECULAR FORMULA :
C3-H7-Cl
MOLECULAR WEIGHT :
78.55

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
5 gm/kg
TOXIC EFFECTS :
Autonomic Nervous System - other (direct) parasympathomimetic Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - cyanosis
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
120 gm/m3
TOXIC EFFECTS :
Blood - changes in leukocyte (WBC) count Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1300 mg/kg
TOXIC EFFECTS :
Autonomic Nervous System - other (direct) parasympathomimetic Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - cyanosis
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
119 gm/m3
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
236 gm/m3/30M/1W-I
TOXIC EFFECTS :
Liver - other changes

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
1 gm/plate
REFERENCE :
DTESD7 52 Vanderbilt Ave., New York, NY 10017) V.1-15, 1977-87. Discontinued 52 Vanderbilt Ave., New York, NY 10017) V.1- 1977- Volume(issue)/page/year: 2,249,1977 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X5379 No. of Facilities: 3 (estimated) No. of Industries: 1 No. of Occupations: 6 No. of Employees: 145 (estimated) No. of Female Employees: 3 (estimated)

 Safety Information

Symbol GHS02 GHS05 GHS07
GHS02, GHS05, GHS07
Signal Word Danger
Hazard Statements H224-H290-H302 + H312 + H332
Precautionary Statements P210-P261-P301 + P312 + P330-P302 + P352 + P312-P304 + P340 + P312-P403 + P235
Personal Protective Equipment Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US)
Hazard Codes F:Flammable;Xn:Harmful;
Risk Phrases R11;R20/21/22
Safety Phrases S9-S29
RIDADR UN 2456 3/PG 1
WGK Germany 3
RTECS UC7200000
Packaging Group I
Hazard Class 3
HS Code 2903199000

 Synthetic Route

 Customs

HS Code 2903199000
Summary 2903199000 other saturated chlorinated derivatives of acyclic hydrocarbons。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

 Synonyms

isopropylchloride
MFCD00000859
2-Propylchloride
iso-C3H7Cl
Narcosop
2-chloro-propan
i-propyl chloride
Propane-2-chloro
Isoprid
2-CHLOROPROPENE
EINECS 209-187-5
2-monochloropropane
2-Chlorpropan
R280da
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