Bovine adrenal medulla dodecapeptide
Bovine adrenal medulla dodecapeptide structure
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Common Name | Bovine adrenal medulla dodecapeptide | ||
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| CAS Number | 75513-71-2 | Molecular Weight | 1424.63000 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C62H97N21O16S | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
Use of Bovine adrenal medulla dodecapeptideBAM-12P, an endogenous opioid peptide, is a novel pro-Met-enkephalin. BAM-12P can activate human κ-opioid receptor (hKOR) with an EC50 of 101 nM and a pEC50 of 6.99. BAM-12P is a ligand for CXCR7 with an EC50 of 175 nM[1][2][3]. |
| Name | bam-12p |
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| Synonym | More Synonyms |
| Description | BAM-12P, an endogenous opioid peptide, is a novel pro-Met-enkephalin. BAM-12P can activate human κ-opioid receptor (hKOR) with an EC50 of 101 nM and a pEC50 of 6.99. BAM-12P is a ligand for CXCR7 with an EC50 of 175 nM[1][2][3]. |
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| Related Catalog | |
| Target |
human κ-opioid receptor (hKOR):101 nM (EC50) human κ-opioid receptor (hKOR):6.99 (pEC50) CXCR7:175 nM (EC50) |
| In Vitro | BAM-12P 在豚鼠回肠试验中显示出有效的阿片活性，IC50 为 15.5 nM[2]。 |
| References |
| Molecular Formula | C62H97N21O16S |
|---|---|
| Molecular Weight | 1424.63000 |
| Exact Mass | 1423.71000 |
| PSA | 643.16000 |
| LogP | 2.50620 |
| Storage condition | -20°C |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| RIDADR | NONH for all modes of transport |
| WGK Germany | 3.0 |
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Substrate specificity of a novel serine protease from soybean [Glycine max (L.) Merrill].
J. Biochem. 119(6) , 1094-9, (1996) The substrate specificity of a novel serine protease isolated from soybean seeds, cultivar Keburi, was investigated using various peptide-MCAs and several neuropeptides involving single and paired bas... |
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Opioid activity of pro-enkephalin-derived peptides in mouse vas deferens and guinea pig ileum.
Neurosci. Lett. 61(3) , 267-71, (1985) The inhibitory activity of several pro-enkephalin A-derived opioid peptides, containing the sequence of Met-enkephalin, was evaluated in two isolated organ preparations sensitive to opioids, the guine... |
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A new family of endogenous "big" Met-enkephalins from bovine adrenal medulla: purification and structure of docosa- (BAM-22P) and eicosapeptide (BAM-20P) with very potent opiate activity.
Biochem. Biophys. Res. Commun. 97 , 1283, (1980)
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| BOVINE ADRENAL MEDULLA-12P |
| TYR-GLY-GLY-PHE-MET-ARG-ARG-VAL-GLY-ARG-PRO-GLU |
| H-TYR-GLY-GLY-PHE-MET-ARG-ARG-VAL-GLY-ARG-PRO-GLU-OH |
| Peptide E(1-12) |
| BOVINE ADRENAL MEDULLA DOCOSAPEPTIDE |
| BOVINE ANDRENAL MEDULLA DODECAPEPTIDE |
| YGGFMRRVGRPE |
| BOVINE ADRENAL MEDULLA DODECAPEPTIDE |