Boc-NH-PEG4-CH2CH2COOH

Modify Date: 2024-01-02 21:02:32

Boc-NH-PEG4-CH2CH2COOH structure	Common Name	Boc-NH-PEG4-CH2CH2COOH
	CAS Number	756525-91-4	Molecular Weight	365.419
	Density	1.1±0.1 g/cm3	Boiling Point	504.5±50.0 °C at 760 mmHg
	Molecular Formula	C₁₆H₃₁NO₈	Melting Point	N/A
	MSDS	Chinese USA	Flash Point	258.9±30.1 °C

Use of Boc-NH-PEG4-CH2CH2COOH

Boc-NH-PEG4-CH2CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTAC[1]. Boc-NH-PEG4-CH2CH2COOH is also a cleavable ADC linker used as a linker for antibody-drug conjugates (ADC)[2].

Name	3-[2-[2-[2-[2-[(2-methylpropan-2-yl)oxycarbonylamino]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
Synonym	More Synonyms

Description	Boc-NH-PEG4-CH2CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTAC[1]. Boc-NH-PEG4-CH2CH2COOH is also a cleavable ADC linker used as a linker for antibody-drug conjugates (ADC)[2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs Alkyl/ether
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
References	[1]. Nathanael Gray, et al. Bifunctional compounds for her3 degradation and methods of use. WO2018114798A1. [2]. Hans-Georg Lerchen, et al. Prodrugs of cytotoxic active agents having enzymatically cleavable groups. WO2018114798A1.

Density	1.1±0.1 g/cm3
Boiling Point	504.5±50.0 °C at 760 mmHg
Molecular Formula	C₁₆H₃₁NO₈
Molecular Weight	365.419
Flash Point	258.9±30.1 °C
Exact Mass	365.204956
PSA	112.55000
LogP	-0.14
Vapour Pressure	0.0±2.8 mmHg at 25°C
Index of Refraction	1.466

Boc-NH-PEG4-CH2CH2COOH MSDS(Chinese)

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR	NONH for all modes of transport

15-T-BUTYLOXYCARBONYLAMINO-4,7,10,13-TETRAOXA-PENTADECANOIC ACID

2,2-Dimethyl-4-oxo-3,8,11,14,17-pentaoxa-5-azaicosan-20-oic acid

3,8,11,14,17-Pentaoxa-5-azaeicosan-20-oic acid, 2,2-dimethyl-4-oxo-

AmbotzPEG1920

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Boc-NH-PEG4-CH2CH2COOH
Price: ￥1680.0/500mg ￥450.0/100mg
Purity: 97.0%
Stocking Period: Inquiry
Contact: Liu jia

Chengdu Pukang Biotechnology Co., Ltd.
China
Product Name: Boc-NH-PEG4-CH2CH2COOH
Price: ￥Inquiry/10g
Purity: 95.0%
Stocking Period: Inquiry
Contact: Lihua Yang

DC Chemicals Limited
China
Product Name: Boc-NH-PEG4-CH2CH2COOH
Price:
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: BOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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