Phe-Pro

Modify Date: 2025-08-25 13:29:02

Phe-Pro Structure
Phe-Pro structure
Common Name Phe-Pro
CAS Number 7669-65-0 Molecular Weight 262.30400
Density N/A Boiling Point N/A
Molecular Formula C14H18N2O3 Melting Point 127-129℃
MSDS Chinese USA Flash Point N/A

 Use of Phe-Pro


(S)-1-((S)-2-Amino-3-phenylpropanoyl)pyrrolidine-2-carboxylic acid is a proline derivative[1].

 Names

Name 1-(2-amino-3-phenylpropanoyl)pyrrolidine-2-carboxylic acid
Synonym More Synonyms

 Phe-Pro Biological Activity

Description (S)-1-((S)-2-Amino-3-phenylpropanoyl)pyrrolidine-2-carboxylic acid is a proline derivative[1].
Related Catalog
In Vitro Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].
References

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

 Chemical & Physical Properties

Melting Point 127-129℃
Molecular Formula C14H18N2O3
Molecular Weight 262.30400
Exact Mass 262.13200
PSA 83.63000
LogP 1.27020
InChIKey WEQJQNWXCSUVMA-RYUDHWBXSA-N
SMILES NC(Cc1ccccc1)C(=O)N1CCCC1C(=O)O
Storage condition -20°C

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
RIDADR NONH for all modes of transport
WGK Germany 3.0
HS Code 2933990090

 Synthetic Route

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Phe-Pro Structure

Phe-Pro

CAS#:7669-65-0

Literature: Xiang, Dao Feng; Patskovsky, Yury; Xu, Chengfu; Fedorov, Alexander A.; Fedorov, Elena V.; Sisco, Abby A.; Sauder, J. Michael; Burley, Stephen K.; Almo, Steven C.; Raushel, Frank M. Biochemistry, 2010 , vol. 49, # 31 p. 6791 - 6803

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Phe-Pro Structure

Phe-Pro

CAS#:7669-65-0

Detail
Literature: Yan; Ho; Hou Bioscience, biotechnology, and biochemistry, 1992 , vol. 56, # 5 p. 704 - 707

~%

Phe-Pro Structure

Phe-Pro

CAS#:7669-65-0

Detail
Literature: Heiduschka; Dittrich; Heins; Neubert; Barth Pharmazie, 1989 , vol. 44, # 11 p. 778 - 780

 Precursor & DownStream

Precursor  2

DownStream  0

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles4

More Articles
Determination of the cis-trans isomerization barrier of several L-peptidyl-L-proline dipeptides by dynamic capillary electrophoresis and computer simulation.

Electrophoresis 22 , 2409-2415, (2001)

Dynamic capillary electrophoresis (DCE) and computer simulation of the elution profiles with the theoretical plate and the stochastic model has been applied to determine the isomerization barriers of ...

Biological evaluation of RBx-0128, a potent and selective dipeptidyl peptidase-IV inhibitor in type 2 diabetes genetic model.

Indian J. Pharmacol. 44(6) , 759-64, (2012)

Dipeptidyl peptidase IV (DPP-IV) inhibition to modulate the incretin effect is a proven strategy to treat type 2 diabetes mellitus. The present study describes the pharmacological profile of a novel D...

Determination of the cis-trans isomerization barrier of enalaprilat by dynamic capillary electrophoresis and computer simulation.

Electrophoresis 25 , 318-323, (2004)

Dynamic capillary electrophoresis (DCE) and computer simulation of the elution profiles with the stochastic model has been applied to determine the isomerization barriers of the angiotensin converting...

 Phe-ProBioassay

View more

Name: Inhibition of ACE (unknown origin)
Source: ChEMBL
Target: Angiotensin-converting enzyme
External Id: CHEMBL3363246
Name: Bitter threshold value
Source: ChEMBL
Target: N/A
External Id: CHEMBL848034
Name: TP_TRANSPORTER: uptake in Xenopus laevis oocytes
Source: ChEMBL
Target: Solute carrier family 15 member 1
External Id: CHEMBL2077579
Name: Inhibition constant (Ki) for human intestinal peptide carrier
Source: ChEMBL
Target: Solute carrier family 15 member 1
External Id: CHEMBL699705
Name: Partition coefficient (logP)
Source: ChEMBL
Target: N/A
External Id: CHEMBL636806
Name: Inhibition of rabbit lung ACE preincubated for 5 mins by spectrophotometric assay
Source: ChEMBL
Target: Angiotensin-converting enzyme
External Id: CHEMBL1810334
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 Synonyms

L-phenylalanyl-L-proline
Phe-Pro
Phenylalanylproline
H-Phe-Pro-OH
L-Phe-L-Pro
L-phenylalanine-L-Proline
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