SL 0101-1 structure
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Common Name | SL 0101-1 | ||
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CAS Number | 77307-50-7 | Molecular Weight | 516.451 | |
Density | 1.6±0.1 g/cm3 | Boiling Point | 753.0±60.0 °C at 760 mmHg | |
Molecular Formula | C25H24O12 | Melting Point | 128-132ºC | |
MSDS | N/A | Flash Point | 255.6±26.4 °C |
Use of SL 0101-1SL 0101-1 (SL0101), a kaempferol glycoside, isolated from the tropical plant F. refracta, is a cell-permeable, selective, reversible, ATP-competitive p90 Ribosomal S6 Kinase (RSK) inhibitor, with an IC50 of 89 nM. Shows proliferation inhibition in human breast cancer cell line MCF-7 and produces a cell cycle block in G1 phase[1]. |
Name | Kaempferol-3-O-(3,4-di-O-acetyl-alpha-L-rhamnopyranoside) |
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Synonym | More Synonyms |
Description | SL 0101-1 (SL0101), a kaempferol glycoside, isolated from the tropical plant F. refracta, is a cell-permeable, selective, reversible, ATP-competitive p90 Ribosomal S6 Kinase (RSK) inhibitor, with an IC50 of 89 nM. Shows proliferation inhibition in human breast cancer cell line MCF-7 and produces a cell cycle block in G1 phase[1]. |
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Related Catalog | |
Target |
IC50: 89 nM (RSK)[1]. |
References |
Density | 1.6±0.1 g/cm3 |
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Boiling Point | 753.0±60.0 °C at 760 mmHg |
Melting Point | 128-132ºC |
Molecular Formula | C25H24O12 |
Molecular Weight | 516.451 |
Flash Point | 255.6±26.4 °C |
Exact Mass | 516.126770 |
PSA | 182.19000 |
LogP | 2.75 |
Vapour Pressure | 0.0±2.6 mmHg at 25°C |
Index of Refraction | 1.666 |
Storage condition | -20℃ |
Precursor 9 | |
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DownStream 1 | |
4H-1-Benzopyran-4-one, 3-[(3,4-di-O-acetyl-6-deoxy-α-L-mannopyranosyl)oxy]-5,7-dihydroxy-2-(4-hydroxyphenyl)- |
3',4'-Di-O-acetylafzelin |
5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-3-yl 3,4-di-O-acetyl-6-deoxy-α-L-mannopyranoside |
3",4"-Diacetylafezelin |
SL 0101-1 |
SL0101 |