Yakuchinone A
Modify Date: 2024-01-12 10:59:48
Yakuchinone A structure
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Common Name | Yakuchinone A | ||
|---|---|---|---|---|
| CAS Number | 78954-23-1 | Molecular Weight | 312.40 | |
| Density | 1.095g/cm3 | Boiling Point | 495.8ºC at 760 mmHg | |
| Molecular Formula | C20H24O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 174.3ºC | |
Use of Yakuchinone AYakuchinone A is a natural product isolated from the fruit of Alpinia oxyphylla, which can induce apoptosis and has anticancer and anti-inflammatory activities[1]. |
| Name | 1-(4'-hydroxy-3'-methoxyphenyl)-7-phenyl-3-heptanone |
|---|---|
| Synonym | More Synonyms |
| Description | Yakuchinone A is a natural product isolated from the fruit of Alpinia oxyphylla, which can induce apoptosis and has anticancer and anti-inflammatory activities[1]. |
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| Related Catalog | |
| In Vitro | Yakuchinone A 作用于 A375P、B16F1、B16F10、A549、MCF-7 和 HT-29 细胞系的 IC50 值分别是 14.75、31.73、21.71、26.07 、11.50 和 11.96[1]。 Yakuchinone A (0-64 μM, 16 h) 可以剂量依赖性方式减少 IL-17 的产生，在 EL4（小鼠淋巴瘤细胞系）细胞中的 IC50 值为 11.5 μM[2] 。 |
| In Vivo | Yakuchinone A (50 mg/kg, i.p., daily, 14 days) 在自身免疫性脑脊髓炎 (EAE) 小鼠模型中可以减轻小鼠的 EAE 症状[1]。 Animal Model: Female C57BL/6 mice[1] Dosage: 50 mg/kg Administration: i.p., daily, 14 days Result: Showed a significant EAE score reduction from Day 9 to Day 15 after EAE onset. |
| References |
| Density | 1.095g/cm3 |
|---|---|
| Boiling Point | 495.8ºC at 760 mmHg |
| Molecular Formula | C20H24O3 |
| Molecular Weight | 312.40 |
| Flash Point | 174.3ºC |
| Exact Mass | 312.17300 |
| PSA | 46.53000 |
| LogP | 4.31550 |
| Index of Refraction | 1.559 |
| Storage condition | 2-8°C |
| yakuchinone-A |
| 1-(4-Hydroxy-3-methoxyphenyl)-7-phenyl-3-heptanone |
| yadanzioside-N |