|   Pempidine structure | Common Name | Pempidine | ||
|---|---|---|---|---|
| CAS Number | 79-55-0 | Molecular Weight | 155.28000 | |
| Density | 0.858 g/mL at 25 °C(lit.) | Boiling Point | 187-188 °C(lit.) | |
| Molecular Formula | C10H21N | Melting Point | 137-141ºC | |
| MSDS | Chinese USA | Flash Point | 122 °F | |
| Symbol |     GHS02, GHS06 | Signal Word | Danger | |
| Use of PempidinePempidine is a ganglion-blocking drug, introduced as an oral treatment for hypertension. | 
| Name | 1,2,2,6,6-pentamethylpiperidine | 
|---|---|
| Synonym | More Synonyms | 
| Description | Pempidine is a ganglion-blocking drug, introduced as an oral treatment for hypertension. | 
|---|---|
| Related Catalog | |
| References | 
| Density | 0.858 g/mL at 25 °C(lit.) | 
|---|---|
| Boiling Point | 187-188 °C(lit.) | 
| Melting Point | 137-141ºC | 
| Molecular Formula | C10H21N | 
| Molecular Weight | 155.28000 | 
| Flash Point | 122 °F | 
| Exact Mass | 155.16700 | 
| PSA | 3.24000 | 
| LogP | 2.59720 | 
| Index of Refraction | n20/D 1.460(lit.) | 
| Storage condition | Flammables area | 
| CHEMICAL IDENTIFICATION
 
 
 
 
 
 
 
 HEALTH HAZARD DATAACUTE TOXICITY DATA
 
 
 
 
 
 
 
 
 
 
 
 | 
| Symbol |     GHS02, GHS06 | 
|---|---|
| Signal Word | Danger | 
| Hazard Statements | H226-H301-H315-H319-H335 | 
| Precautionary Statements | P261-P301 + P310-P305 + P351 + P338 | 
| Personal Protective Equipment | Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter | 
| Hazard Codes | Xn: Harmful; | 
| Risk Phrases | R10 | 
| Safety Phrases | S26-S36/37 | 
| RIDADR | UN 1992 3/PG 3 | 
| WGK Germany | 3 | 
| RTECS | TN2190000 | 
| Packaging Group | III | 
| Hazard Class | 3 | 
| HS Code | 2933399090 | 
| ~75%   Pempidine CAS#:79-55-0 | 
| Literature: Caliskan, Hafize; Zaim, Oemer Synthetic Communications, 2010 , vol. 40, # 20 p. 3078 - 3083 | 
| ~80%   Pempidine CAS#:79-55-0 | 
| Literature: Rae, Ian D.; Woolcock, Mark L. Australian Journal of Chemistry, 1990 , vol. 43, # 2 p. 447 - 450 | 
| ~31%   Pempidine CAS#:79-55-0 | 
| Literature: Kostyanovskii, R. G.; Shakhgel'diev, M. A.; Nabiev, O. G. Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1986 , vol. 35, # 12 p. 2593 Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1986 , # 12 p. 2826 - 2827 | 
| ~%   Pempidine CAS#:79-55-0 | 
| Literature: US4208525 A1, ; | 
| ~%   Pempidine CAS#:79-55-0 | 
| Literature: Journal of the American Chemical Society, , vol. 79, p. 5279,5286 | 
| ~%   Pempidine CAS#:79-55-0 | 
| Literature: Journal of the American Chemical Society, , vol. 79, p. 5439 | 
| ~%   Pempidine CAS#:79-55-0 | 
| Literature: Journal of the American Chemical Society, , vol. 134, # 42 p. 17384 - 17387 | 
| ~%   Pempidine CAS#:79-55-0 | 
| Literature: Bulletin of the Chemical Society of Japan, , vol. 68, # 5 p. 1401 - 1408 | 
| Precursor 7 | |
|---|---|
| DownStream 9 | |
| HS Code | 2933399090 | 
|---|---|
| Summary | 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% | 
| Pharmacological characterization of a nicotinic autoreceptor in rat hippocampal synaptosomes. Neurochem. Res. 21(9) , 1141-8, (1996) The modulation of [3H]ACh release by nicotinic compounds was studied in superfused rat hippocampal synaptosomes loaded with [3H]choline, (-)-Nicotine (0.1-10 microM) evoked a dose-dependent increase i... | |
| Enhancement of naturally occurring cell death in the sympathetic and parasympathetic ganglia of the chicken embryo following blockade of ganglionic transmission. Brain Res. 444(1) , 189-94, (1988) Both presynaptic and postsynaptic blockade of ganglionic transmission during the period of naturally occurring ganglion cell death reduced the number of surviving neurons in the sympathetic ganglia (S... | |
| Understanding channel blocking in the nicotinic acetylcholine receptor. Receptors Channels 7(4) , 273-88, (2001) Ion-channel blockers are molecules that obstruct the path used by ions to cross the membrane through a protein channel. Many of these are local anesthetics, toxins or drugs of abuse, and the knowledge... | 
| PIPERIDINE,1,2,2,6,6-PENTAMETHYL | 
| Pyrilene | 
| MFCD00006493 | 
| N-methyl-2,2,6,6-tetramethylpiperidine | 
| Perolysen | 
| EINECS 201-211-2 | 
| M+B 4486 | 
| Pempidine | 
| N,2,2,6,6-pentamethyl piperidine |