Pempidine structure
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Common Name | Pempidine | ||
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CAS Number | 79-55-0 | Molecular Weight | 155.28000 | |
Density | 0.858 g/mL at 25 °C(lit.) | Boiling Point | 187-188 °C(lit.) | |
Molecular Formula | C10H21N | Melting Point | 137-141ºC | |
MSDS | Chinese USA | Flash Point | 122 °F | |
Symbol |
GHS02, GHS06 |
Signal Word | Danger |
Use of PempidinePempidine is a ganglion-blocking drug, introduced as an oral treatment for hypertension. |
Name | 1,2,2,6,6-pentamethylpiperidine |
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Synonym | More Synonyms |
Description | Pempidine is a ganglion-blocking drug, introduced as an oral treatment for hypertension. |
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Related Catalog | |
References |
Density | 0.858 g/mL at 25 °C(lit.) |
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Boiling Point | 187-188 °C(lit.) |
Melting Point | 137-141ºC |
Molecular Formula | C10H21N |
Molecular Weight | 155.28000 |
Flash Point | 122 °F |
Exact Mass | 155.16700 |
PSA | 3.24000 |
LogP | 2.59720 |
Index of Refraction | n20/D 1.460(lit.) |
Storage condition | Flammables area |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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Symbol |
GHS02, GHS06 |
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Signal Word | Danger |
Hazard Statements | H226-H301-H315-H319-H335 |
Precautionary Statements | P261-P301 + P310-P305 + P351 + P338 |
Personal Protective Equipment | Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
Hazard Codes | Xn: Harmful; |
Risk Phrases | R10 |
Safety Phrases | S26-S36/37 |
RIDADR | UN 1992 3/PG 3 |
WGK Germany | 3 |
RTECS | TN2190000 |
Packaging Group | III |
Hazard Class | 3 |
HS Code | 2933399090 |
~75% Pempidine CAS#:79-55-0 |
Literature: Caliskan, Hafize; Zaim, Oemer Synthetic Communications, 2010 , vol. 40, # 20 p. 3078 - 3083 |
~80% Pempidine CAS#:79-55-0 |
Literature: Rae, Ian D.; Woolcock, Mark L. Australian Journal of Chemistry, 1990 , vol. 43, # 2 p. 447 - 450 |
~31% Pempidine CAS#:79-55-0 |
Literature: Kostyanovskii, R. G.; Shakhgel'diev, M. A.; Nabiev, O. G. Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1986 , vol. 35, # 12 p. 2593 Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1986 , # 12 p. 2826 - 2827 |
~% Pempidine CAS#:79-55-0 |
Literature: US4208525 A1, ; |
~% Pempidine CAS#:79-55-0 |
Literature: Journal of the American Chemical Society, , vol. 79, p. 5279,5286 |
~% Pempidine CAS#:79-55-0 |
Literature: Journal of the American Chemical Society, , vol. 79, p. 5439 |
~% Pempidine CAS#:79-55-0 |
Literature: Journal of the American Chemical Society, , vol. 134, # 42 p. 17384 - 17387 |
~% Pempidine CAS#:79-55-0 |
Literature: Bulletin of the Chemical Society of Japan, , vol. 68, # 5 p. 1401 - 1408 |
Precursor 7 | |
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DownStream 9 | |
HS Code | 2933399090 |
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Summary | 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Pharmacological characterization of a nicotinic autoreceptor in rat hippocampal synaptosomes.
Neurochem. Res. 21(9) , 1141-8, (1996) The modulation of [3H]ACh release by nicotinic compounds was studied in superfused rat hippocampal synaptosomes loaded with [3H]choline, (-)-Nicotine (0.1-10 microM) evoked a dose-dependent increase i... |
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Enhancement of naturally occurring cell death in the sympathetic and parasympathetic ganglia of the chicken embryo following blockade of ganglionic transmission.
Brain Res. 444(1) , 189-94, (1988) Both presynaptic and postsynaptic blockade of ganglionic transmission during the period of naturally occurring ganglion cell death reduced the number of surviving neurons in the sympathetic ganglia (S... |
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Understanding channel blocking in the nicotinic acetylcholine receptor.
Receptors Channels 7(4) , 273-88, (2001) Ion-channel blockers are molecules that obstruct the path used by ions to cross the membrane through a protein channel. Many of these are local anesthetics, toxins or drugs of abuse, and the knowledge... |
PIPERIDINE,1,2,2,6,6-PENTAMETHYL |
Pyrilene |
MFCD00006493 |
N-methyl-2,2,6,6-tetramethylpiperidine |
Perolysen |
EINECS 201-211-2 |
M+B 4486 |
Pempidine |
N,2,2,6,6-pentamethyl piperidine |