Paeoniflorigenone
Modify Date: 2024-01-02 11:51:13
Paeoniflorigenone structure
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Common Name | Paeoniflorigenone | ||
|---|---|---|---|---|
| CAS Number | 80454-42-8 | Molecular Weight | 318.321 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 481.1±45.0 °C at 760 mmHg | |
| Molecular Formula | C17H18O6 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 177.1±22.2 °C | |
Use of PaeoniflorigenonePaeoniflorigenone, isolated as an active ingredient from the root of moutan cortex, induces apoptosis selectively in the cancer cell lines and exhibits antiproliferative effect[1]. |
| Name | Paeoniflorigenone |
|---|---|
| Synonym | More Synonyms |
| Description | Paeoniflorigenone, isolated as an active ingredient from the root of moutan cortex, induces apoptosis selectively in the cancer cell lines and exhibits antiproliferative effect[1]. |
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| Related Catalog | |
| In Vitro | Paeoniflorigenone (0-30 μM; 0-72 hours) significantly decreases the cell proliferation of tumor cell lines and inhibits the proliferation of normal cell lines[1]. Paeoniflorigenone (0-30 μM; 24-72 hours) significantly induces apoptotic DNA fragmentation selectively in tumor cells[1]. Cell Proliferation Assay[1] Cell Line: TIG-1, 3T3-L1, HL60, Jurkat and HeLa cells Concentration: 0-30 μM Incubation Time: 0-72 hours Result: Significantly decreased the cell proliferation of tumor cell lines and inhibited the proliferation of normal cell lines. Apoptosis Analysis[1] Cell Line: TIG-1 and 3T3-L1 (normal cells), HL60, Jurkat, and HeLa cells (tumor cells) Concentration: 0, 1, 3, 10, 30 μM Incubation Time: 24 and 72 hours Result: Induced DNA fragmentation in three tumor cell lines, but not in two normal cell lines. |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 481.1±45.0 °C at 760 mmHg |
| Molecular Formula | C17H18O6 |
| Molecular Weight | 318.321 |
| Flash Point | 177.1±22.2 °C |
| Exact Mass | 318.110352 |
| PSA | 82.06000 |
| LogP | 2.87 |
| Vapour Pressure | 0.0±1.3 mmHg at 25°C |
| Index of Refraction | 1.605 |
| Hazard Codes | Xi |
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