![]() Melanin structure
|
Common Name | Melanin | ||
---|---|---|---|---|
CAS Number | 8049-97-6 | Molecular Weight | 318.28300 | |
Density | 1.65g/cm3 | Boiling Point | 500.5ºC at 760 mmHg | |
Molecular Formula | C18H10N2O4 | Melting Point | N/A | |
MSDS | Chinese USA | Flash Point | 195.4ºC |
Use of MelaninMelanin is a unique pigment with myriad functions. It is multifunctional, providing defense against environmental stresses such as ultraviolet (UV) light, oxidizing agents and ionizing radiation. |
Name | Melanin |
---|---|
Synonym | More Synonyms |
Description | Melanin is a unique pigment with myriad functions. It is multifunctional, providing defense against environmental stresses such as ultraviolet (UV) light, oxidizing agents and ionizing radiation. |
---|---|
Related Catalog | |
Target |
Human Endogenous Metabolite |
In Vitro | Melanin contributes to the ability of fungi to survive in harsh environments. In addition, it plays a role in fungal pathogenesis. Melanin is an amorphous polymer that is produced by one of two synthetic pathways. Fungi may synthesize melanin from endogenous substrate via a 1,8-dihydroxynaphthalene (DHN) intermediate. Alternatively, some fungi produce melanin from L-3,4-dihydroxyphenylalanine (L-dopa)[1]. |
References |
Density | 1.65g/cm3 |
---|---|
Boiling Point | 500.5ºC at 760 mmHg |
Molecular Formula | C18H10N2O4 |
Molecular Weight | 318.28300 |
Flash Point | 195.4ºC |
Exact Mass | 318.06400 |
PSA | 99.86000 |
LogP | 1.32660 |
Index of Refraction | 1.771 |
Storage condition | -20°C |
Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
---|---|
Hazard Codes | Xi |
RIDADR | NONH for all modes of transport |
WGK Germany | 1 |
HS Code | 3203001990 |
HS Code | 3203001990 |
---|
Testing in mice the hypothesis that melanin is protective in malaria infections.
PLoS ONE 7 , e29493, (2012) Malaria has had the largest impact of any infectious disease on shaping the human genome, exerting enormous selective pressure on genes that improve survival in severe malaria infections. Modern human... |
|
Identification of quinolines that inhibit melanogenesis by altering tyrosinase family trafficking.
Mol. Pharmacol. 74 , 1576-86, (2009) A series of quinolines, including chloroquine and quinine, were identified as potent pigmentation inhibitors through screening a compound library in murine melanocytes. Structure-activity relationship... |
|
Ex vivomodels to evaluate the role of ocular melanin in trans-scleral drug delivery
Eur. J. Pharm. Sci. 46(5) , 475-83, (2012) Trans-scleral delivery is nowadays considered as a possible way to deliver drugs to the posterior segment of the eye. Despite the potentiality of this administration route, there is a lack of fundamen... |
EINECS 232-473-6 |
MFCD00131581 |