Melanin

Modify Date: 2024-01-02 20:40:55

Melanin Structure
Melanin structure
Common Name Melanin
CAS Number 8049-97-6 Molecular Weight 318.28300
Density 1.65g/cm3 Boiling Point 500.5ºC at 760 mmHg
Molecular Formula C18H10N2O4 Melting Point N/A
MSDS Chinese USA Flash Point 195.4ºC

 Use of Melanin


Melanin is a unique pigment with myriad functions. It is multifunctional, providing defense against environmental stresses such as ultraviolet (UV) light, oxidizing agents and ionizing radiation.

 Names

Name Melanin
Synonym More Synonyms

 Melanin Biological Activity

Description Melanin is a unique pigment with myriad functions. It is multifunctional, providing defense against environmental stresses such as ultraviolet (UV) light, oxidizing agents and ionizing radiation.
Related Catalog
Target

Human Endogenous Metabolite

In Vitro Melanin contributes to the ability of fungi to survive in harsh environments. In addition, it plays a role in fungal pathogenesis. Melanin is an amorphous polymer that is produced by one of two synthetic pathways. Fungi may synthesize melanin from endogenous substrate via a 1,8-dihydroxynaphthalene (DHN) intermediate. Alternatively, some fungi produce melanin from L-3,4-dihydroxyphenylalanine (L-dopa)[1].
References

[1]. Eisenman HC, et al. Synthesis and assembly of fungal melanin. Appl Microbiol Biotechnol. 2012 Feb;93(3):931-40.

 Chemical & Physical Properties

Density 1.65g/cm3
Boiling Point 500.5ºC at 760 mmHg
Molecular Formula C18H10N2O4
Molecular Weight 318.28300
Flash Point 195.4ºC
Exact Mass 318.06400
PSA 99.86000
LogP 1.32660
Index of Refraction 1.771
Storage condition -20°C

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
RIDADR NONH for all modes of transport
WGK Germany 1
HS Code 3203001990

 Customs

HS Code 3203001990

 Articles8

More Articles
Testing in mice the hypothesis that melanin is protective in malaria infections.

PLoS ONE 7 , e29493, (2012)

Malaria has had the largest impact of any infectious disease on shaping the human genome, exerting enormous selective pressure on genes that improve survival in severe malaria infections. Modern human...

Identification of quinolines that inhibit melanogenesis by altering tyrosinase family trafficking.

Mol. Pharmacol. 74 , 1576-86, (2009)

A series of quinolines, including chloroquine and quinine, were identified as potent pigmentation inhibitors through screening a compound library in murine melanocytes. Structure-activity relationship...

Ex vivomodels to evaluate the role of ocular melanin in trans-scleral drug delivery

Eur. J. Pharm. Sci. 46(5) , 475-83, (2012)

Trans-scleral delivery is nowadays considered as a possible way to deliver drugs to the posterior segment of the eye. Despite the potentiality of this administration route, there is a lack of fundamen...

 Synonyms

EINECS 232-473-6
MFCD00131581
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