L-Glutamic acid-5-13C

Modify Date: 2024-01-02 18:04:56

L-Glutamic acid-5-13C structure	Common Name	L-Glutamic acid-5-13C
	CAS Number	81202-00-8	Molecular Weight	148.12200
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₄₁₃CH₉NO₄	Melting Point	205ºC (dec.)(lit.)
	MSDS	Chinese USA	Flash Point	N/A

Use of L-Glutamic acid-5-13C

L-Glutamic acid-5-13C is the 13C-labeled L-Glutamic acid. L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). L-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals.

Name	(2S)-2-aminopentanedioic acid
Synonym	More Synonyms

Description	L-Glutamic acid-5-13C is the 13C-labeled L-Glutamic acid. L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). L-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals.
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In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.