Ganoderic acid B

Modify Date: 2024-01-04 16:19:35

Ganoderic acid B structure	Common Name	Ganoderic acid B
	CAS Number	81907-61-1	Molecular Weight	516.666
	Density	1.2±0.1 g/cm3	Boiling Point	689.0±55.0 °C at 760 mmHg
	Molecular Formula	C₃₀H₄₄O₇	Melting Point	N/A
	MSDS	Chinese	Flash Point	384.4±28.0 °C

Use of Ganoderic acid B

Ganoderic acid B is a triterpene isolated from a mushroom Ganoderma lucidum. Ganoderic acid B inhibits the activation of Epstein-Barr virus (EBV) antigens as telomerase inhibitor. Ganoderic acid B is a moderately active inhibitor against HIV-1 protease[1][2][3].

Name	(2R,6R)-6-[(3S,5R,7S,10S,13R,14R,17R)-3,7-dihydroxy-4,4,10,13,14-pentamethyl-11,15-dioxo-2,3,5,6,7,12,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methyl-4-oxoheptanoic acid
Synonym	More Synonyms

Description	Ganoderic acid B is a triterpene isolated from a mushroom Ganoderma lucidum. Ganoderic acid B inhibits the activation of Epstein-Barr virus (EBV) antigens as telomerase inhibitor. Ganoderic acid B is a moderately active inhibitor against HIV-1 protease[1][2][3].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Metabolic Enzyme/Protease >> HIV Protease
Target	HIV-1 protease[3]
References	[1]. Zhou S, et al. Triterpenes and Soluble Polysaccharide Changes in Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), During Fruiting Growth. Int J Med Mushrooms. 2018;20(9):859-871. [2]. Zheng DS, et al. Triterpenoids from Ganoderma lucidum inhibit the activation of EBV antigens as telomerase inhibitors. Exp Ther Med. 2017 Oct;14(4):3273-3278. [3]. el-Mekkawy S, et al. Anti-HIV-1 and anti-HIV-1-protease substances from Ganoderma lucidum. Phytochemistry. 1998 Nov;49(6):1651-7.

Density	1.2±0.1 g/cm3
Boiling Point	689.0±55.0 °C at 760 mmHg
Molecular Formula	C₃₀H₄₄O₇
Molecular Weight	516.666
Flash Point	384.4±28.0 °C
Exact Mass	516.308716
PSA	128.97000
LogP	2.33
Vapour Pressure	0.0±4.9 mmHg at 25°C
Index of Refraction	1.565
Storage condition	-20C