Di-Paralene
Di-Paralene structure
|
Common Name | Di-Paralene | ||
|---|---|---|---|---|
| CAS Number | 82-93-9 | Molecular Weight | 300.82600 | |
| Density | N/A | Boiling Point | 137-145ºC at 0.1-0.15 MM HG | |
| Molecular Formula | C18H21ClN2 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS07, GHS09 |
Signal Word | Warning | |
Use of Di-ParaleneChlorcyclizine is a first-generation antihistamine of the phenylpiperazine class marketed in the United States and certain other countries. It is used primarily to treat allergy symptoms such as rhinitis, urticaria, and pruritus, and may also be used as an antiemetic. In addition to its antihistamine effects, chlorcyclizine also has some anticholinergic, antiserotonergic, and local anesthetic properties. It also has been studied as a potential treatment for hepatitis C. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine |
|---|---|
| Synonym | More Synonyms |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Boiling Point | 137-145ºC at 0.1-0.15 MM HG |
|---|---|
| Molecular Formula | C18H21ClN2 |
| Molecular Weight | 300.82600 |
| Exact Mass | 300.13900 |
| PSA | 6.48000 |
| LogP | 3.55260 |
| InChIKey | WFNAKBGANONZEQ-UHFFFAOYSA-N |
| SMILES | CN1CCN(C(c2ccccc2)c2ccc(Cl)cc2)CC1 |
This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
MUTATION DATA
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This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Symbol |
GHS07, GHS09 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302-H400 |
| Precautionary Statements | P301 + P312 + P330 |
| RIDADR | UN 3077 9 / PGIII |
| HS Code | 2933599090 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
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~54%
Di-Paralene CAS#:82-93-9 |
| Literature: Sengmany, Stephane; Le Gall, Erwan; Le Jean, Cedric; Troupel, Michel; Nedelec, Jean-Yves Tetrahedron, 2007 , vol. 63, # 18 p. 3672 - 3681 |
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~%
Di-Paralene CAS#:82-93-9 |
| Literature: Journal of the American Chemical Society, , vol. 71, p. 2731,2732 Journal of Organic Chemistry, , vol. 14, p. 775,777, 779 |
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~34%
Di-Paralene CAS#:82-93-9 |
| Literature: Sengmany, Stephane; Le Gall, Erwan; Le Jean, Cedric; Troupel, Michel; Nedelec, Jean-Yves Tetrahedron, 2007 , vol. 63, # 18 p. 3672 - 3681 |
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~%
Di-Paralene CAS#:82-93-9 |
| Literature: Venkat Narsaiah; Narsimha Medicinal Chemistry Research, 2012 , vol. 21, # 4 p. 538 - 541 |
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~%
Di-Paralene CAS#:82-93-9 |
| Literature: Medicinal Chemistry Research, , vol. 21, # 4 p. 538 - 541 |
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~%
Di-Paralene CAS#:82-93-9 |
| Literature: Medicinal Chemistry Research, , vol. 21, # 4 p. 538 - 541 |
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~%
Di-Paralene CAS#:82-93-9 |
| Literature: Medicinal Chemistry Research, , vol. 21, # 4 p. 538 - 541 |
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~%
Di-Paralene CAS#:82-93-9 |
| Literature: US2861072 , ; |
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 10 | |
|---|---|
| DownStream 0 | |
This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2933599090 |
|---|---|
| Summary | 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| Trihistan |
| Chlorcycline |
| Chlorocycline |
| Alergicide |
| Histantine |
| Diparalene |
| 1-(4-chloro-benzhydryl)-4-methyl-piperazine |
| Histachlorazene |
| chlorcyclizine |
| Perazyl |
| 1-[(4-chlorophenyl)(phenyl)methyl]-4-methylpiperazine |
| Chlorocyclizine |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the molecular weight of 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine? |
| A: Molecular weight of 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine is 300.82600. |
| Q: What is the SMILES notation of 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine? |
| A: SMILES notation of 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine is CN1CCN(C(c2ccccc2)c2ccc(Cl)cc2)CC1. |
| Q: What is the LogP of 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine? |
| A: LogP of 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine is 3.55260. |
| Q: What is the CAS number of 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine? |
| A: CAS number of 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine is 82-93-9. |
| Q: What is the boiling point of 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine? |
| A: Boiling point of 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine is 137-145ºC at 0.1-0.15 MM HG. |
| Q: What is the InChIKey of 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine? |
| A: InChIKey of 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine is WFNAKBGANONZEQ-UHFFFAOYSA-N. |
| Q: What English synonyms does 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine have? |
| A: English synonyms of 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine: Trihistan, Chlorcycline, Chlorocycline, Alergicide, Histantine, Diparalene, 1-(4-chloro-benzhydryl)-4-methyl-piperazine, Histachlorazene, chlorcyclizine, Perazyl, 1-[(4-chlorophenyl)(phenyl)methyl]-4-methylpiperazine, Chlorocyclizine. |
| Q: What is the molecular formula of 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine? |
| A: Molecular formula of 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine is C18H21ClN2. |
| Q: What is the English name of 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine? |
| A: The English name of 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine is 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine. |
| Q: What is the polar surface area (PSA) of 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine? |
| A: Polar surface area (PSA) of 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine is 6.48000. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |