sophoridine

Modify Date: 2024-01-03 14:02:30

sophoridine Structure
sophoridine structure
Common Name sophoridine
CAS Number 83148-91-8 Molecular Weight 248.36
Density 1.164 g/cm3 Boiling Point 396.738ºC at 760 mmHg
Molecular Formula C15H24N2O Melting Point N/A
MSDS N/A Flash Point 172.748ºC

 Use of sophoridine


d-Sophoridine ((+)-Sophoridine) is the dextro isoform of Sophoridine (HY-N1373), which is a quinolizidine alkaloid isolated from Leguminous plant Sophora flavescens. Sophoridine induces apoptosis. Sophoridine has the potential to be a novel, potent and selective antitumor agent candidate for pancreatic cancer with well-tolerated toxicity[1].

 Names

Name Sophoridine
Synonym More Synonyms

 sophoridine Biological Activity

Description d-Sophoridine ((+)-Sophoridine) is the dextro isoform of Sophoridine (HY-N1373), which is a quinolizidine alkaloid isolated from Leguminous plant Sophora flavescens. Sophoridine induces apoptosis. Sophoridine has the potential to be a novel, potent and selective antitumor agent candidate for pancreatic cancer with well-tolerated toxicity[1].
Related Catalog
References

[1]. Xu Z, et al. Sophoridine induces apoptosis and S phase arrest via ROS-dependent JNK and ERK activation in human pancreatic cancer cells. J Exp Clin Cancer Res. 2017 Sep 11;36(1):124.  

 Chemical & Physical Properties

Density 1.164 g/cm3
Boiling Point 396.738ºC at 760 mmHg
Molecular Formula C15H24N2O
Molecular Weight 248.36
Flash Point 172.748ºC
Exact Mass 248.18900
PSA 23.55000
LogP 1.74750

 Synonyms

matridin-15-one
(2R,3R)-2,3-bis(4-hydroxy-3-methoxybenzyl)-4-butanolide
S-GINSENOSIDE RG3
(2R,3R)-2,3-bis(4-hydroxy-3-methoxybenzyl)butyrolactone
(3R,4R)-rel-Dihydro-3,4-bis[(4-hydroxy-3-methoxyphenyl)methyl]-2(3H)-furanone
(E)-3,4-di[(4-hydroxy-3-methoxyphenyl)methyl]dihydro-2(3H)-furanone
SOPHORIDINE (REFERENCE GRADE)
MATRIDIN-15-ONE, (6B,7B,11A)-
rac Matairesinol
(8R,8'R)-(-)-matairesinol
Allomatrine
trans-Dihydro-3,4-bis[(4-hydroxy-3-methoxyphenyl)methyl]-2(3H)-furanone