1-naphthylamine-5-sulfonic acid structure
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Common Name | 1-naphthylamine-5-sulfonic acid | ||
|---|---|---|---|---|
| CAS Number | 84-89-9 | Molecular Weight | 223.248 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C10H9NO3S | Melting Point | >300°C | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS05, GHS07 |
Signal Word | Danger | |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 5-Aminonaphthalene-1-sulfonic acid |
|---|---|
| Synonym | More Synonyms |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Melting Point | >300°C |
| Molecular Formula | C10H9NO3S |
| Molecular Weight | 223.248 |
| Exact Mass | 223.030319 |
| PSA | 88.77000 |
| LogP | 0.42 |
| Index of Refraction | 1.713 |
| InChIKey | DQNAQOYOSRJXFZ-UHFFFAOYSA-N |
| SMILES | Nc1cccc2c(S(=O)(=O)O)cccc12 |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Symbol |
GHS05, GHS07 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H312-H314-H332 |
| Precautionary Statements | P280-P305 + P351 + P338-P310 |
| Personal Protective Equipment | Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges |
| Hazard Codes | C:Corrosive; |
| Risk Phrases | R20/21/22;R34 |
| Safety Phrases | S26-S36/37/39-S45 |
| RIDADR | UN 2585 8/PG 3 |
| WGK Germany | 3 |
| RTECS | QK1270500 |
| Packaging Group | III |
| Hazard Class | 8 |
| HS Code | 2921450090 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 9 | |
|---|---|
| DownStream 10 | |
This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2921450090 |
|---|---|
| Summary | 2921450090 1-naphthylamine (α-naphthylamine), 2-naphthylamine (β-naphthylamine) and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0% |
This table lists relevant public references with title, journal and publication metadata for this compound.
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Identification of a novel ligand binding motif in the transthyretin channel.
Bioorg. Med. Chem. 18 , 100-10, (2010) The design of therapeutic compounds targeting transthyretin (TTR) is challenging due to the low specificity of interaction in the hormone binding site. Such feature is highlighted by the interactions ... |
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[An interesting peroxidase staining.--utilization of blended substrate of mixed 2, 7-FDA and Laurent's acid-- (author's transl)].
Rinsho Byori. 29(6) , 613-6, (1981)
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Evidence for a ppGpp-binding site on Escherichia coli RNA polymerase: proximity relationship with the rifampicin-binding domain.
Mol. Microbiol. 15(2) , 255-65, (1995) On amino acid starvation, Escherichia coli cells exhibit an adaptive facility termed the stringent response. This is characterized by the production of high levels of a regulatory nucleotide, ppGpp, a... |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
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Name: Binding affinity to human recombinant TTR T119M mutant denominated hormone binding si...
Source: ChEMBL
Target: N/A
External Id: CHEMBL1070798
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Name: Inhibition of wild type human TTR aggregation expressed in Escherichia coli assessed ...
Source: ChEMBL
Target: Transthyretin
External Id: CHEMBL1070799
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Name: NCI human tumor cell line growth inhibition assay. Data for the MCF7 Non-Small Cell L...
Source: DTP/NCI
Target: N/A
External Id: MCF7_OneDose
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Name: Binding affinity to wild type human TTR denominated hormone binding site expressed in...
Source: ChEMBL
Target: Transthyretin
External Id: CHEMBL1070796
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Name: Binding affinity to human recombinant TTR V30M mutant denominated hormone binding sit...
Source: ChEMBL
Target: Transthyretin
External Id: CHEMBL1070797
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Name: NCI human tumor cell line growth inhibition assay. Data for the IGROV1 Non-Small Cell...
Source: DTP/NCI
Target: N/A
External Id: IGROV1_OneDose
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This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| 1-naphthylamine-5-sulfonic acid |
| 5-Amino-1-naphthalenesulfonic acid |
| 5-Aminonaphthalene-1-sulfonic acid |
| MFCD00014315 |
| EINECS 201-571-0 |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the melting point of 5-Aminonaphthalene-1-sulfonic acid? |
| A: Melting point of 5-Aminonaphthalene-1-sulfonic acid is >300°C. |
| Q: What is the SMILES notation of 5-Aminonaphthalene-1-sulfonic acid? |
| A: SMILES notation of 5-Aminonaphthalene-1-sulfonic acid is Nc1cccc2c(S(=O)(=O)O)cccc12. |
| Q: What is the safety information for 5-Aminonaphthalene-1-sulfonic acid? |
| A: Safety information for 5-Aminonaphthalene-1-sulfonic acid: S26-S36/37/39-S45. |
| Q: What is the English name of 5-Aminonaphthalene-1-sulfonic acid? |
| A: The English name of 5-Aminonaphthalene-1-sulfonic acid is 5-Aminonaphthalene-1-sulfonic acid. |
| Q: What English synonyms does 5-Aminonaphthalene-1-sulfonic acid have? |
| A: English synonyms of 5-Aminonaphthalene-1-sulfonic acid: 1-naphthylamine-5-sulfonic acid, 5-Amino-1-naphthalenesulfonic acid, 5-Aminonaphthalene-1-sulfonic acid, MFCD00014315, EINECS 201-571-0. |
| Q: What is the polar surface area (PSA) of 5-Aminonaphthalene-1-sulfonic acid? |
| A: Polar surface area (PSA) of 5-Aminonaphthalene-1-sulfonic acid is 88.77000. |
| Q: What is the molecular weight of 5-Aminonaphthalene-1-sulfonic acid? |
| A: Molecular weight of 5-Aminonaphthalene-1-sulfonic acid is 223.248. |
| Q: What is the LogP of 5-Aminonaphthalene-1-sulfonic acid? |
| A: LogP of 5-Aminonaphthalene-1-sulfonic acid is 0.42. |
| Q: What is the CAS number of 5-Aminonaphthalene-1-sulfonic acid? |
| A: CAS number of 5-Aminonaphthalene-1-sulfonic acid is 84-89-9. |
| Q: What is the InChIKey of 5-Aminonaphthalene-1-sulfonic acid? |
| A: InChIKey of 5-Aminonaphthalene-1-sulfonic acid is DQNAQOYOSRJXFZ-UHFFFAOYSA-N. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |