Wilforlide A

Modify Date: 2024-01-02 08:57:32

Wilforlide A Structure
Wilforlide A structure
Common Name Wilforlide A
CAS Number 84104-71-2 Molecular Weight 454.684
Density 1.1±0.1 g/cm3 Boiling Point 555.0±50.0 °C at 760 mmHg
Molecular Formula C30H46O3 Melting Point 318 °C
MSDS N/A Flash Point 208.6±22.9 °C

 Use of Wilforlide A


Wilforlide A is a natural product, separated from the ethanolic extract of tripterygium wilfordii. IC50 value:Target:In vitro:In vivo: Carrageenan-induced rat pedal swelling, tampon-induced rat granulation, and mice ear inhibition rate of swelling trail results show that high-dose wilforlide A has obvious anti-inflammatory effect, but has no significant immune suppressive activity [1].

 Names

Name wilforlide a
Synonym More Synonyms

 Wilforlide A Biological Activity

Description Wilforlide A is a natural product, separated from the ethanolic extract of tripterygium wilfordii. IC50 value:Target:In vitro:In vivo: Carrageenan-induced rat pedal swelling, tampon-induced rat granulation, and mice ear inhibition rate of swelling trail results show that high-dose wilforlide A has obvious anti-inflammatory effect, but has no significant immune suppressive activity [1].
Related Catalog
References

[1]. Mei Xue, et al. Comparative study on the anti-inflammatory and immune suppressive effect of Wilforlide A. Fitoterapia Volume 81, Issue 8, December 2010, Pages 1109–1112

[2]. HU Jian-lin, et al. Determination of Wilforlide A in Tripterygium hypoglaucum (Levl.) Hutch by HPLC. Journal of Kunming Medical College, 2010-07

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 555.0±50.0 °C at 760 mmHg
Melting Point 318 °C
Molecular Formula C30H46O3
Molecular Weight 454.684
Flash Point 208.6±22.9 °C
Exact Mass 454.344696
PSA 46.53000
LogP 7.47
Vapour Pressure 0.0±3.4 mmHg at 25°C
Index of Refraction 1.563

 Safety Information

Hazard Codes C

 Precursor & DownStream

Precursor  0

DownStream  1

 Synonyms

Olean-12-en-29-one, 22,29-epoxy-3-hydroxy-, (3β,22α)-
WOLFORLIDE A
(3β,22α)-3-Hydroxy-22,29-epoxyolean-12-en-29-one
Regelide
Wilforlide
WilforlideA
abruslactone A
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