NCH 51
Modify Date: 2024-01-08 11:23:27
NCH 51 structure
|
Common Name | NCH 51 | ||
|---|---|---|---|---|
| CAS Number | 848354-66-5 | Molecular Weight | 390.563 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C20H26N2O2S2 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS05 |
Signal Word | Danger | |
Use of NCH 51PTACH (NCH-51) is a SAHA-based novel inhibitor of human HDAC. PTACH exerts potent growth inhibition against various human cancer cells, with EC50 values ranging from 1 to 10 μM.IC50 value: 1-10 μM (EC50)Target: HDACin vitro: In cancer cell growth inhibition assay, PTACH shows strong activity. PTACH inhibits various cancer cells with EC50 of 2.3, 9.1, 3.0, 2.6, 1.1, 4.5, 2.4, 5.0, and 4.5 μM for MDA-MB-231 breast cancer, SNB-78 central nervous system, HCT116 colon cancer, NCI-H226 lung cancer, LOX-IMVI melanoma, SK-OV-3 ovarian cancer, RXF-631L renal cancer, St-4 stomach cancer, and DU-145 prostate cancer. |
| Name | S-[7-oxo-7-[(4-phenyl-1,3-thiazol-2-yl)amino]heptyl] 2-methylpropanethioate |
|---|---|
| Synonym | More Synonyms |
| Description | PTACH (NCH-51) is a SAHA-based novel inhibitor of human HDAC. PTACH exerts potent growth inhibition against various human cancer cells, with EC50 values ranging from 1 to 10 μM.IC50 value: 1-10 μM (EC50)Target: HDACin vitro: In cancer cell growth inhibition assay, PTACH shows strong activity. PTACH inhibits various cancer cells with EC50 of 2.3, 9.1, 3.0, 2.6, 1.1, 4.5, 2.4, 5.0, and 4.5 μM for MDA-MB-231 breast cancer, SNB-78 central nervous system, HCT116 colon cancer, NCI-H226 lung cancer, LOX-IMVI melanoma, SK-OV-3 ovarian cancer, RXF-631L renal cancer, St-4 stomach cancer, and DU-145 prostate cancer. |
|---|---|
| Related Catalog | |
| Target |
HDAC |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Molecular Formula | C20H26N2O2S2 |
| Molecular Weight | 390.563 |
| Exact Mass | 390.143555 |
| PSA | 112.60000 |
| LogP | 5.49 |
| Appearance of Characters | white solid |
| Index of Refraction | 1.588 |
| Storage condition | -20℃ |
| Symbol |
GHS05 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H318-H413 |
| Precautionary Statements | P280-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi: Irritant; |
| Risk Phrases | 41 |
| Safety Phrases | 26-39 |
| RIDADR | NONH for all modes of transport |
| HS Code | 2934100090 |
| HS Code | 2934100090 |
|---|---|
| Summary | 2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0% |
| Propanethioic acid, 2-methyl-, S-[7-oxo-7-[(4-phenyl-2-thiazolyl)amino]heptyl] ester |
| NCH 51 |
| Cpd 51 |
| PTACH |
| S-{7-Oxo-7-[(4-phenyl-1,3-thiazol-2-yl)amino]heptyl} 2-methylpropanethioate |
| thioisobutyric acid S-(6-(4-phenyl-2-thiazolylcarbamoyl)hexyl) ester |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: NCH-51
- Price: Negotiable
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Huang
- Email: sales@echemcloud.com
- DC Chemicals Limited
- China
- Product Name: PTACH (NCH-51)
- Price: $200.0/5mg
- Purity: 98.0%
- Delivery: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
- ShangHai DC Chemicals Co.,Ltd
- China
- Product Name: PTACH (NCH-51)
- Price: ￥Inquiry/1g
- Purity: 98.9%
- Delivery: 1 Day
- Contact: Tony Lai
- Email: order@dcchemicals.com
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: S-(7-OXO-7-((4-PHENYLTHIAZOL-2-YL)AMINO)HEPTYL) 2-METHYLPROPANETHIOATE
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Delivery: Inquiry
- Contact: Ms Wang
- Email: enquiry@dycnchem.com
Get all suppliers and price by the below link:
Price: $106/10mM*1mLinDMSO
Reference only. check more NCH 51 price