Phthalylsulfathiazole
Phthalylsulfathiazole structure
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Common Name | Phthalylsulfathiazole | ||
|---|---|---|---|---|
| CAS Number | 85-73-4 | Molecular Weight | 403.432 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 579ºC at 760 mmHg | |
| Molecular Formula | C17H13N3O5S2 | Melting Point | 198-204°C | |
| MSDS | USA | Flash Point | 304ºC | |
Use of PhthalylsulfathiazolePhthalylsulfathiazole is a kind of sulfonamides used as an antibacterial drug. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | Phthalylsulfathiazole |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | Phthalylsulfathiazole is a kind of sulfonamides used as an antibacterial drug. |
|---|---|
| Related Catalog | |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Boiling Point | 579ºC at 760 mmHg |
| Melting Point | 198-204°C |
| Molecular Formula | C17H13N3O5S2 |
| Molecular Weight | 403.432 |
| Flash Point | 304ºC |
| Exact Mass | 403.029663 |
| PSA | 162.08000 |
| LogP | 1.54 |
| Index of Refraction | 1.715 |
| InChIKey | PBMSWVPMRUJMPE-UHFFFAOYSA-N |
| SMILES | O=C(O)c1ccccc1C(=O)Nc1ccc(S(=O)(=O)Nc2nccs2)cc1 |
| Storage condition | -20°C |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| RIDADR | 3249 |
| RTECS | TH8575000 |
| Packaging Group | III |
| Hazard Class | 6.1(b) |
| HS Code | 2935009090 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
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| Literature: CH242247 , ; |
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Phthalylsulfath... CAS#:85-73-4 |
| Literature: Journal of the Chemical Society, , p. 821 |
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Phthalylsulfath... CAS#:85-73-4 |
| Literature: Journal of the Chemical Society, , p. 821 |
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Phthalylsulfath... CAS#:85-73-4 |
| Literature: Journal of the Chemical Society, , p. 821 |
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Phthalylsulfath... CAS#:85-73-4 |
| Literature: Meditsinskaya Promyshlennost SSSR, , vol. 11, # 12 p. 17,20 Chem.Abstr., , p. 15505 |
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 6 | |
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| DownStream 0 | |
This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2935009090 |
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| Summary | 2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0% |
This table lists relevant public references with title, journal and publication metadata for this compound.
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[Experimental basis for the tentative permissible levels of phthalazol, sulfadimethoxine and Bepask in bodies of water].
Gig. Sanit. (12) , 9-10, (1993) Tentative permissible levels (TPL) of phthalazol, sulfadimethoxine, and Bepask in the water were substantiated on the basis of study of organoleptic properties, of influence on sanitary status of wate... |
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The effect of antibacterial agents on the intestinal flora of patients: the use of aureomycin, chloromycetin, dihydrostreptomycin, sulfasuxidine and sulfathalidine.
Gastroenterology 16(1) , 12-8, (1950)
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The effects of phthalylsulphathiazole on the bacteria of the colonic mucosa and intestinal contents as revealed by the examination of surgical samples.
Scand. J. Gastroenterol. 14(7) , 891-6, (1979) The isolation of a bacterial flora specifically associated with the colonic mucosa of patients undergoing large-bowel surgery is described. This flora differed from that of faeces in both the numbers ... |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
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Name: Primary qHTS assay for inhibitors of alpha-synuclein gene (SNCA) expression
Source: NCGC
External Id: SNCA-p-activity-luciferase
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Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
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Name: Cytochrome P450 Family 1 Subfamily A Member 2 (CYP1A2) small molecule antagonists: lu...
Source: 824
External Id: CYP273
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Name: Increase the activity of the Burkholderia fixLJ 2-component system
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: Burkholderia multivorans
External Id: HMS1625
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Name: Fluorescence-based cell-based primary high throughput screening assay to identify pos...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
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Name: qHTS Assay for Small Molecule Inhibitors of the Human hERG Channel Activity
Source: NCGC
External Id: HERG01
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Name: qHTS for Inhibitors of TGF-b: Cytotox Counterscreen
Source: NCGC
Target: N/A
External Id: SMAD3201
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Name: uHTS identification of cystic fibrosis induced NFkb Inhibitors in a fluoresence assay
Source: Burnham Center for Chemical Genomics
Target: cystic fibrosis transmembrane conductance regulator [Homo sapiens]
External Id: SBCCG-A764-CF-PAF-Primary-Assay
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Name: Fluorescence-based cell-based primary high throughput screening assay to identify ant...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_ANT_FLUO8_1536_1X%INH PRUN
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This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| Cremothalidine |
| Phthalylsulfathiazole |
| Taloudron |
| Ftalazol |
| 2-[({4-[(1,3-thiazol-2-ylamino)sulfonyl]phenyl}amino)carbonyl]benzoic acid |
| N-(4-thiazol-2-ylsulfamoyl-phenyl)-phthalamic acid |
| Talidine |
| entexidin |
| Phtalazol |
| N-(4-Thiazol-2-ylsulfamoyl-phenyl)-phthalamidsaeure |
| EINECS 201-627-4 |
| Sulftalyl |
| PST |
| 2-[({4-[(2-thiazolylamino)sulfonyl]phenyl}amino)carbonyl]-benzoic acid |
| Thalinil |
| Ftalysept |
| 2-{[4-(1,3-Thiazol-2-ylsulfamoyl)phenyl]carbamoyl}benzoic acid |
| MFCD00005318 |
| Taleudron |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the SMILES notation of Phthalylsulfathiazole? |
| A: SMILES notation of Phthalylsulfathiazole is O=C(O)c1ccccc1C(=O)Nc1ccc(S(=O)(=O)Nc2nccs2)cc1. |
| Q: What is the InChIKey of Phthalylsulfathiazole? |
| A: InChIKey of Phthalylsulfathiazole is PBMSWVPMRUJMPE-UHFFFAOYSA-N. |
| Q: What is the LogP of Phthalylsulfathiazole? |
| A: LogP of Phthalylsulfathiazole is 1.54. |
| Q: What is the melting point of Phthalylsulfathiazole? |
| A: Melting point of Phthalylsulfathiazole is 198-204°C. |
| Q: What are the uses of Phthalylsulfathiazole? |
| A: Main uses of Phthalylsulfathiazole: Phthalylsulfathiazole is a kind of sulfonamides used as an antibacterial drug. |
| Q: What is the English name of Phthalylsulfathiazole? |
| A: The English name of Phthalylsulfathiazole is Phthalylsulfathiazole. |
| Q: What is the molecular formula of Phthalylsulfathiazole? |
| A: Molecular formula of Phthalylsulfathiazole is C17H13N3O5S2. |
| Q: What are the upstream materials of Phthalylsulfathiazole? |
| A: Related upstream materials(CAS) of Phthalylsulfathiazole: 85-44-9;72-14-0;36340-59-7;520-03-6;4435-59-0;144-74-1. |
| Q: What is the boiling point of Phthalylsulfathiazole? |
| A: Boiling point of Phthalylsulfathiazole is 579ºC at 760 mmHg. |
| Q: What is the molecular weight of Phthalylsulfathiazole? |
| A: Molecular weight of Phthalylsulfathiazole is 403.432. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |
| Henan Tianfu Chemical Co., Ltd. |