3,5-Bis(trifluoromethyl)benzylamine

Modify Date: 2024-01-03 11:48:09

3,5-Bis(trifluoromethyl)benzylamine Structure
3,5-Bis(trifluoromethyl)benzylamine structure
Common Name 3,5-Bis(trifluoromethyl)benzylamine
CAS Number 85068-29-7 Molecular Weight 243.149
Density 1.4±0.1 g/cm3 Boiling Point 165.5±35.0 °C at 760 mmHg
Molecular Formula C9H7F6N Melting Point 50-55 °C(lit.)
MSDS Chinese USA Flash Point 78.3±0.0 °C
Symbol GHS05
GHS05
Signal Word Danger

 Names

Name 3,5-Bis(trifluoromethyl)benzylamine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 165.5±35.0 °C at 760 mmHg
Melting Point 50-55 °C(lit.)
Molecular Formula C9H7F6N
Molecular Weight 243.149
Flash Point 78.3±0.0 °C
Exact Mass 243.048264
PSA 26.02000
LogP 2.51
Vapour Pressure 1.9±0.3 mmHg at 25°C
Index of Refraction 1.420

 Safety Information

Symbol GHS05
GHS05
Signal Word Danger
Hazard Statements H314
Precautionary Statements P280-P305 + P351 + P338-P310
Personal Protective Equipment Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes C:Corrosive;
Risk Phrases R21/22;R34
Safety Phrases S26-S36/37/39-S45
RIDADR UN 3259 8/PG 2
WGK Germany 3
Packaging Group III
Hazard Class 8
HS Code 2921499090

 Synthetic Route

~85%

3,5-Bis(trifluoromethyl)benzylamine Structure

3,5-Bis(trifluo...

CAS#:85068-29-7

Literature: EP1500641 A1, ; Page 12 ;

~99%

3,5-Bis(trifluoromethyl)benzylamine Structure

3,5-Bis(trifluo...

CAS#:85068-29-7

Literature: Organic Letters, , vol. 5, # 7 p. 1007 - 1010

~92%

3,5-Bis(trifluoromethyl)benzylamine Structure

3,5-Bis(trifluo...

CAS#:85068-29-7

Literature: Synlett, , # 10 p. 1623 - 1625

~%

3,5-Bis(trifluoromethyl)benzylamine Structure

3,5-Bis(trifluo...

CAS#:85068-29-7

Literature: Organic Letters, , vol. 5, # 7 p. 1007 - 1010

 Customs

HS Code 2921499090
Summary 2921499090 other aromatic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

 Articles1

More Articles
Discovery of 3,5-bis(trifluoromethyl)benzyl L-arylglycinamide based potent CCR2 antagonists.

Bioorg. Med. Chem. Lett. 16(14) , 3735-9, (2006)

Systematic modification of a screening lead yielded a class of potent glycinamide based CCR2 antagonists. The best compound (55, (2S)-N-[3,5-bis(trifluoromethyl)benzyl]-2-{[2-(1-piperidinyl)ethyl]amin...

 Synonyms

3,5-Di(trifluoromethyl)benzylamine
1-[3,5-Bis(trifluoromethyl)phenyl]methanamine
EINECS 285-290-9
Benzenemethanamine, 3,5-bis(trifluoromethyl)-
FXFFR C1Z EXFFF
MFCD00009909
[3,5-Bis(trifluoromethyl)phenyl]methylamine
3,5-Bis(trifluoromethyl)benzenemethanamine
[3,5-Bis(trifluoromethyl)phenyl]methanamine
3,5-Bis(trifluoromethyl)benzylamine