3,5-Bis(trifluoromethyl)benzaldehyde

Modify Date: 2025-08-22 14:15:57

3,5-Bis(trifluoromethyl)benzaldehyde Structure
3,5-Bis(trifluoromethyl)benzaldehyde structure
Common Name 3,5-Bis(trifluoromethyl)benzaldehyde
CAS Number 401-95-6 Molecular Weight 242.118
Density 1.4±0.1 g/cm3 Boiling Point 188.5±0.0 °C at 760 mmHg
Molecular Formula C9H4F6O Melting Point -2ºC
MSDS Chinese USA Flash Point 57.5±20.1 °C
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name 3,5-Bis(trifluoromethyl)benzaldehyde
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 188.5±0.0 °C at 760 mmHg
Melting Point -2ºC
Molecular Formula C9H4F6O
Molecular Weight 242.118
Flash Point 57.5±20.1 °C
Exact Mass 242.016632
PSA 17.07000
LogP 3.58
Vapour Pressure 0.6±0.3 mmHg at 25°C
Index of Refraction 1.425
InChIKey LDWLIXZSDPXYDR-UHFFFAOYSA-N
SMILES O=Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes Xn:Harmful
Risk Phrases R22;R36/37/38
Safety Phrases S26-S36-S37/39
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2913000090

 Synthetic Route

 Customs

HS Code 2913000090
Summary HS: 2913000090 halogenated, sulphonated, nitrated or nitrosated derivatives of products of heading 2912 Educational tariff:17.0% Tax rebate rate:9.0% Regulatory conditions:none Most favored nation tariff:5.5% General tariff:30.0%

 Articles2

More Articles
Synthesis of a novel 4H-pyran analog as minor groove binder to DNA using ethidium bromide as fluorescence probe.

Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 152 , 165-71, (2015)

In the present work, isopropyl-6-amino-4-(3,5-bis(trifluoromethyl)phenyl)-5-cyano-2-methyl-4H-pyran-3-carboxylate (4H-pyran analog) has been synthesized by a three component reaction catalyzed by CsOH...

meso-3,5-Bis(trifluoromethyl)phenyl-substituted expanded porphyrins: synthesis, characterization, and optical, electrochemical, and photophysical properties.

Chem. Asian J. 3(12) , 2065-74, (2008)

Trifluoroacetic acid-catalyzed condensation of pyrrole with electron-deficient and sterically hindered 3,5-bis(trifluoromethyl)benzaldehyde results in the unexpected production of a series of meso-3,5...

 3,5-Bis(trifluoromethyl)benzaldehydeBioassay

View more

Name: Inhibition of JAK3 (unknown origin) at 100 uM preincubated for 1 hr followed by subst...
Source: ChEMBL
Target: Tyrosine-protein kinase JAK3
External Id: CHEMBL5231773
Name: Inhibition of MAP2K4 (unknown origin) at 100 uM preincubated for 1 hr followed by sub...
Source: ChEMBL
Target: Dual specificity mitogen-activated protein kinase kinase 4
External Id: CHEMBL5231772
Name: Inhibition of MELK (unknown origin) at 100 uM preincubated for 1 hr followed by subst...
Source: ChEMBL
Target: Maternal embryonic leucine zipper kinase
External Id: CHEMBL5231774
Name: Inhibition of BTK (unknown origin) at 100 uM preincubated for 1 hr followed by substr...
Source: ChEMBL
Target: Tyrosine-protein kinase BTK
External Id: CHEMBL5231769
Name: Aqueous stability of the compound assessed as compound degradation by measuring half ...
Source: ChEMBL
Target: N/A
External Id: CHEMBL5231768
Name: Inhibition of RSK2 (unknown origin) at 100 uM preincubated for 1 hr followed by subst...
Source: ChEMBL
Target: Ribosomal protein S6 kinase alpha-3
External Id: CHEMBL5231771
Name: Inhibition of ERK2 (unknown origin) at 100 uM preincubated for 1 hr followed by subst...
Source: ChEMBL
Target: Mitogen-activated protein kinase 1
External Id: CHEMBL5231770
Name: Thiol reactivity of compound assessed as kinetic rate constant by LC-MS analysis
Source: ChEMBL
Target: N/A
External Id: CHEMBL5231765
Name: Aqueous stability of the compound assessed as compound degradation by measuring kinet...
Source: ChEMBL
Target: N/A
External Id: CHEMBL5231767
Name: Thiol reactivity of compound assessed as half life by LC-MS analysis
Source: ChEMBL
Target: N/A
External Id: CHEMBL5231766
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 Synonyms

MFCD00010206
MBT-BAD
3,5-ditrifluoromethylbenzaldehyde
α,α,α,α',α',α'-Hexafluoro-3,5-xylylaldehyde
FXFFR CVH EXFFF
3,5-Di(trifluoromethyl)benzaldehyde
3,5-Bis(trifluoromethyl)benzaldehyde
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