Mannitol

Modify Date: 2024-01-02 13:20:17

Mannitol Structure
Mannitol structure
Common Name Mannitol
CAS Number 87-78-5 Molecular Weight 182.172
Density 1.596 Boiling Point 494.9°C
Molecular Formula C6H14O6 Melting Point 167°C
MSDS Chinese Flash Point 292.5±23.3 °C

 Use of Mannitol


DL-Mannitol is obtained by combining D-mannitol with a sample of Lmannitol obtained by reduction of L-mannono-1, Clactone[1].

 Names

Name Mannitol
Synonym More Synonyms

 Mannitol Biological Activity

Description DL-Mannitol is obtained by combining D-mannitol with a sample of Lmannitol obtained by reduction of L-mannono-1, Clactone[1].
Related Catalog
In Vitro DL-Mannitol is obtained by combining D-mannitol with a sample of L-mannitol obtained by reduction of L-mannono-1, Clactone[1].
References

[1]. Grindley, T. B., et al. Towards understanding 13C-N.M.R. chemical shifts of carbohydrates in the solid state. The spectra of d-mannitol polymorphs and of dl-mannitol. Carbohydrate Research, 197, 41–52.

 Chemical & Physical Properties

Density 1.596
Boiling Point 494.9°C
Melting Point 167°C
Molecular Formula C6H14O6
Molecular Weight 182.172
Flash Point 292.5±23.3 °C
Exact Mass 182.079041
PSA 121.38000
LogP -4.67
Vapour Pressure 0.0±2.8 mmHg at 25°C
Index of Refraction 1.597
Storage condition Inert atmosphere,Room Temperature
Water Solubility 177.3g/L(25 ºC)

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
OP2050000
CHEMICAL NAME :
Mannitol
CAS REGISTRY NUMBER :
87-78-5
LAST UPDATED :
199701
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C6-H14-O6
MOLECULAR WEIGHT :
182.20

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Human - man
DOSE/DURATION :
5714 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Gastrointestinal - nausea or vomiting Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis)
REFERENCE :
NPRNAY Nephron. (S. Karger Pub., Inc., 79 Fifth Ave., New York, NY 10003) V.1- 1964- Volume(issue)/page/year: 45,233,1987

 Safety Information

Safety Phrases S24/25-S22
WGK Germany 3
HS Code 2905430000

 Customs

HS Code 2905430000
Summary HS:2905430000 (2r,3r,4r,5r)-hexane-1,2,3,4,5,6-hexaol VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB MFN tariff:8.0% General tariff:30.0%

 Synonyms

Maitol
MANNITOL B
MFCD00065361
D-glycero-Hexitol
MANNITOL USP
MANNITOL USP 24
EINECS 201-770-2
MANNITOL BP
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