STING agonist C11
Modify Date: 2025-08-24 18:24:57
STING agonist C11 structure
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Common Name | STING agonist C11 | ||
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| CAS Number | 875863-22-2 | Molecular Weight | 382.436 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C19H18N4O3S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of STING agonist C11STING agonist C11 is a novel cell-permeable STING agonist that activates IFN-dependent signaling processes and induces IFN secretion from human cells; induces transcription and translation of interferon-dependent antiviral genes, induces canonical IRF3 phosphorylation and ISG transcription in a manner that requires STING but not MAVS or TRIF; potently blocks replication of multiple emerging Alphavirus types including Chikungunya, Ross River, Mayaro, and O'nyong'nyong viruses. |
| Name | N-(Methylcarbamoyl)-2-{[5-(4-methylphenyl)-1,3,4-oxadiazol-2-yl]sulfanyl}-2-phenylacetamide |
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| Synonym | More Synonyms |
| Description | STING agonist C11 is a novel cell-permeable STING agonist that activates IFN-dependent signaling processes and induces IFN secretion from human cells; induces transcription and translation of interferon-dependent antiviral genes, induces canonical IRF3 phosphorylation and ISG transcription in a manner that requires STING but not MAVS or TRIF; potently blocks replication of multiple emerging Alphavirus types including Chikungunya, Ross River, Mayaro, and O'nyong'nyong viruses. |
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| References | References 1. Gall B, et al. J Virol. 2017 Dec 20. pii: JVI.01913-17. View Related Products by Target STING |
| Density | 1.4±0.1 g/cm3 |
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| Molecular Formula | C19H18N4O3S |
| Molecular Weight | 382.436 |
| Exact Mass | 382.109955 |
| LogP | 4.73 |
| Index of Refraction | 1.650 |
| Benzeneacetamide, N-[(methylamino)carbonyl]-α-[[5-(4-methylphenyl)-1,3,4-oxadiazol-2-yl]thio]- |
| N-(Methylcarbamoyl)-2-{[5-(4-methylphenyl)-1,3,4-oxadiazol-2-yl]sulfanyl}-2-phenylacetamide |