PSNCBAM-1

Modify Date: 2025-10-05 12:14:17

PSNCBAM-1 structure	Common Name	PSNCBAM-1
	CAS Number	877202-74-9	Molecular Weight	392.88100
	Density	N/A	Boiling Point	521.5±50.0 °C(Predicted)
	Molecular Formula	C₂₂H₂₁ClN₄O	Melting Point	N/A
	MSDS	Chinese USA	Flash Point	N/A
	Symbol	GHS07	Signal Word	Warning

Use of PSNCBAM-1

PSNCBAM-1 is a selective CB1 receptor allosteric antagonist with an EC50 of 0.1 μM. PSNCBAM-1 can be used in the researches of obesity[1].

Name	Urea, N-(4-chlorophenyl)-N'-[3-[6-(1-pyrrolidinyl)-2-pyridinyl]phenyl]
Synonym	More Synonyms

Description	PSNCBAM-1 is a selective CB1 receptor allosteric antagonist with an EC50 of 0.1 μM. PSNCBAM-1 can be used in the researches of obesity[1].
Related Catalog	Research Areas >> Metabolic Disease Signaling Pathways >> GPCR/G Protein >> Cannabinoid Receptor
Target	hCB1-R:0.1 μM (EC50)
References	[1]. Horswill JG, et al. PSNCBAM-1, a novel allosteric antagonist at cannabinoid CB1 receptors with hypophagic effects in rats. Br J Pharmacol. 2007 Nov;152(5):805-14.

Boiling Point	521.5±50.0 °C(Predicted)
Molecular Formula	C₂₂H₂₁ClN₄O
Molecular Weight	392.88100
Exact Mass	392.14000
PSA	57.26000
LogP	5.85720
InChIKey	HDAYFSFWIPRJSO-UHFFFAOYSA-N
SMILES	O=C(Nc1ccc(Cl)cc1)Nc1cccc(-c2cccc(N3CCCC3)n2)c1
Storage condition	2-8°C

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302-H319
Precautionary Statements	P305 + P351 + P338
RIDADR	NONH for all modes of transport

Name: Thermal Shift Assay. Domain: start/stop: M1-L298
Source: ChEMBL
Target: Cyclin-dependent kinase 2
External Id: CHEMBL5062802

Name: Negative allosteric modulator activity at human CB1R expressed in CHO-K1 cells assess...
Source: ChEMBL
Target: Cannabinoid receptor 1
External Id: CHEMBL3760354

Name: Negative allosteric modulator activity at human CB1R expressed in CHO-K1 cells assess...
Source: ChEMBL
Target: Cannabinoid receptor 1
External Id: CHEMBL3760353

Name: Negative allosteric modulator activity at human CB1R expressed in CHO-K1 cells assess...
Source: ChEMBL
Target: Cannabinoid receptor 1
External Id: CHEMBL3760352

Name: Allosteric modulation of CB1 receptor (unknown origin) assessed as inhibition of CP55...
Source: ChEMBL
Target: Cannabinoid receptor 1
External Id: CHEMBL4329660

Name: Agonist activity at CB1 receptor (unknown origin) relative to CP55940
Source: ChEMBL
Target: Cannabinoid receptor 1
External Id: CHEMBL4329659

Name: Allosteric modulation of CB1 receptor (unknown origin) assessed as inhibition of calc...
Source: ChEMBL
Target: Cannabinoid receptor 1
External Id: CHEMBL4329658

Name: Primary qHTS to identify gynecologic anti-cancer compounds using libraries of approve...
Source: NCGC
Target: N/A
External Id: OBG420

Name: Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of Cac...
Source: ChEMBL
Target: Severe acute respiratory syndrome coronavirus 2
External Id: CHEMBL4303805

Name: Negative allosteric modulator activity at human CB1R expressed in CHO-K1 cells assess...
Source: ChEMBL
Target: Cannabinoid receptor 1
External Id: CHEMBL3760355

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PSNCBAM 1

1-(4-Chlorophenyl)-3-[3-[6-(pyrrolidin-1-yl)pyridin-2-yl]phenyl]urea

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: PSNCBAM-1
Price: Check
Purity: 99.0%
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 1-(4-Chlorophenyl)-3-[3-[6-(pyrrolidin-1-yl)pyridin-2-yl]phenyl]urea
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.