2-Benzylsuccinic acid

Modify Date: 2024-01-02 23:18:57

2-Benzylsuccinic acid structure	Common Name	2-Benzylsuccinic acid
	CAS Number	884-33-3	Molecular Weight	208.211
	Density	1.3±0.1 g/cm3	Boiling Point	331.4±22.0 °C at 760 mmHg
	Molecular Formula	C₁₁H₁₂O₄	Melting Point	161-163°C
	MSDS	Chinese USA	Flash Point	168.4±18.8 °C

Use of 2-Benzylsuccinic acid

2-Benzylsuccinic acid (DL-Benzylsuccinic acid) is an potent inhibitor of carboxypeptidase A (CPA)[1].

Name	2-benzylsuccinic acid
Synonym	More Synonyms

Description	2-Benzylsuccinic acid (DL-Benzylsuccinic acid) is an potent inhibitor of carboxypeptidase A (CPA)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Carboxypeptidase
References	[1]. Mark P. Wentland, et al. 96-Well Plate Colorimetric Assay for Ki Determination of (+/-)-2-Benzylsuccinic Acid, an Inhibitor of Carboxypeptidase A: A Laboratory Experiment in Drug Discovery. J Chem Educ. 2004 Mar 1, 81 (3):398.

Density	1.3±0.1 g/cm3
Boiling Point	331.4±22.0 °C at 760 mmHg
Melting Point	161-163°C
Molecular Formula	C₁₁H₁₂O₄
Molecular Weight	208.211
Flash Point	168.4±18.8 °C
Exact Mass	208.073563
PSA	74.60000
LogP	1.60
Vapour Pressure	0.0±0.8 mmHg at 25°C
Index of Refraction	1.568

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Risk Phrases	36/37/38
Safety Phrases	S26-S36
RIDADR	NONH for all modes of transport
WGK Germany	3
HS Code	2917399090

HS Code	2917399090
Summary	2917399090 aromatic polycarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Regulation of cytoplasmic tubulin carboxypeptidase activity in vitro by cations and sulfhydryl-modifying compounds.

J. Cell. Biochem. 60(3) , 424-36, (1996)

alpha-tubulin subunits within microtubules (MTs) can be post-translationally detyrosinated by a tubulin-specific carboxypeptidase (TCP) activity to form biochemically distinct MTs. Attempts to charact...

Nerve injury evoked loss of latexin expression in spinal cord neurons contributes to the development of neuropathic pain.

PLoS ONE 6(4) , e19270, (2011)

Nerve injury leads to sensitization mechanisms in the peripheral and central nervous system which involve transcriptional and post-transcriptional modifications in sensory nerves. To assess protein re...

The three-dimensional structure of human procarboxypeptidase A2. Deciphering the basis of the inhibition, activation and intrinsic activity of the zymogen.

EMBO J. 16(23) , 6906-13, (1997)

The three-dimensional structure of human procarboxypeptidase A2 has been determined using X-ray crystallography at 1.8 A resolution. This is the first detailed structural report of a human pancreatic ...

Butanedioic acid, 2-(phenylmethyl)-

2-Benzylsuccinic acid

Benzyl butanedioic acid

DL-BENZYLSUCCINIC ACID

alpha-Benzylsuccinic acid

2-benzylbutanedioic acid

MFCD00055798