SARS-CoV-IN-3
Modify Date: 2024-01-09 16:13:09
SARS-CoV-IN-3 structure
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Common Name | SARS-CoV-IN-3 | ||
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| CAS Number | 888958-27-8 | Molecular Weight | 469.74 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C25H20ClFeN3O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of SARS-CoV-IN-3SARS-CoV-IN-3 is an effective inhibitor of SARS-CoV replication. SARS-CoV-IN-3 shows anti-Coronavirus activity with an EC50 of 3.6 μM in Vero cells. SARS-CoV-IN-3 inhibits the 3D7 and W2 strains of P. falciparum with IC50s of 11.7 and 20.4 nM; and IC90s of 29.19 and 56 nM; respectively. SARS-CoV-IN-3 reduces HIV-1-induced cytopathic effect with an EC50 of 10 μM in MT-4 cells[1]. |
| Name | SARS-CoV-IN-3 |
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| Description | SARS-CoV-IN-3 is an effective inhibitor of SARS-CoV replication. SARS-CoV-IN-3 shows anti-Coronavirus activity with an EC50 of 3.6 μM in Vero cells. SARS-CoV-IN-3 inhibits the 3D7 and W2 strains of P. falciparum with IC50s of 11.7 and 20.4 nM; and IC90s of 29.19 and 56 nM; respectively. SARS-CoV-IN-3 reduces HIV-1-induced cytopathic effect with an EC50 of 10 μM in MT-4 cells[1]. |
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| Related Catalog | |
| Target |
EC50: 3.6 μM (SARS-CoV, in Vero cells)[1] IC50: 11.7 nM (3D7 P. falciparum), 20.4 nM (W2 P. falciparum)[1] IC90: 29.19 nM (3D7 P. falciparum), 56 nM (W2 P. falciparum)[1] |
| In Vitro | SARS-CoV-IN-3 (Compound 4) inhibits in vitro growth of Plasmodium falciparum far better than Chloroquine (CQ) [1]. |
| References |
| Molecular Formula | C25H20ClFeN3O |
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| Molecular Weight | 469.74 |