SARS-CoV-IN-2
Modify Date: 2024-01-09 23:05:14
SARS-CoV-IN-2 structure
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Common Name | SARS-CoV-IN-2 | ||
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| CAS Number | 888958-26-7 | Molecular Weight | 455.72 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C24H18ClFeN3O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of SARS-CoV-IN-2SARS-CoV-IN-2 is an effective inhibitor of SARS-CoV replication. SARS-CoV-IN-2 shows anti-Coronavirus activity with an EC50 of 1.9 μM in Vero cells. SARS-CoV-IN-2 inhibits the 3D7 and W2 strains of P. falciparum with IC50s of 21.5 and 30 nM; and IC90s of 51.0 and 99.9 nM; respectively. SARS-CoV-IN-2 reduces HIV-1-induced cytopathic effect with an EC50 of 2.9 μM in MT-4 cells. Antimalarial and Antiviral Activities[1]. |
| Name | SARS-CoV-IN-2 |
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| Description | SARS-CoV-IN-2 is an effective inhibitor of SARS-CoV replication. SARS-CoV-IN-2 shows anti-Coronavirus activity with an EC50 of 1.9 μM in Vero cells. SARS-CoV-IN-2 inhibits the 3D7 and W2 strains of P. falciparum with IC50s of 21.5 and 30 nM; and IC90s of 51.0 and 99.9 nM; respectively. SARS-CoV-IN-2 reduces HIV-1-induced cytopathic effect with an EC50 of 2.9 μM in MT-4 cells. Antimalarial and Antiviral Activities[1]. |
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| Related Catalog | |
| Target |
EC50: 1.9 μM (SARS-CoV, in Vero cells)[1] IC50: 21.5 nM (3D7 P. falciparum), 30 nM (W2 P. falciparum)[1] IC90: 51.0 nM (3D7 P. falciparum), 99.9 nM (W2 P. falciparum)[1] |
| In Vitro | SARS-CoV-IN-2 (Compound 3) inhibits in vitro growth of Plasmodium falciparum far better than Chloroquine (CQ) [1]. |
| References |
| Molecular Formula | C24H18ClFeN3O |
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| Molecular Weight | 455.72 |