4-Chloro-2-nitroaniline

Modify Date: 2026-07-03 13:29:38

4-Chloro-2-nitroaniline structure	Common Name	4-Chloro-2-nitroaniline
	CAS Number	89-63-4	Molecular Weight	172.569
	Density	1.5±0.1 g/cm3	Boiling Point	308.8±22.0 °C at 760 mmHg
	Molecular Formula	C₆H₅ClN₂O₂	Melting Point	117-119 °C(lit.)
	MSDS	Chinese USA	Flash Point	140.5±22.3 °C
	Symbol	GHS06, GHS08, GHS09	Signal Word	Danger

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name	4-Chloro-2-nitroaniline
Synonym	More Synonyms

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density	1.5±0.1 g/cm3
Boiling Point	308.8±22.0 °C at 760 mmHg
Melting Point	117-119 °C(lit.)
Molecular Formula	C₆H₅ClN₂O₂
Molecular Weight	172.569
Flash Point	140.5±22.3 °C
Exact Mass	172.003952
PSA	71.84000
LogP	2.74
Vapour Pressure	0.0±0.7 mmHg at 25°C
Index of Refraction	1.646
InChIKey	PBGKNXWGYQPUJK-UHFFFAOYSA-N
SMILES	Nc1ccc(Cl)cc1[N+](=O)[O-]
Water Solubility	INSOLUBLE

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

4-Chloro-2-nitroaniline MSDS(Chinese)

This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.

CHEMICAL IDENTIFICATION

RTECS NUMBER :: BX1575000

CHEMICAL NAME :: Aniline, 4-chloro-2-nitro-

CAS REGISTRY NUMBER :: 89-63-4

BEILSTEIN REFERENCE NO. :: 0512436

LAST UPDATED :: 199710

DATA ITEMS CITED :: 14

MOLECULAR FORMULA :: C6-H5-Cl-N2-O2

MOLECULAR WEIGHT :: 172.58

WISWESSER LINE NOTATION :: ZR DG BNW

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 400 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 800 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 63 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 3 gm/kg

TOXIC EFFECTS :: Behavioral - general anesthetic

MUTATION DATA

TYPE OF TEST :: Sister chromatid exchange

TEST SYSTEM :: Rodent - hamster Ovary

DOSE/DURATION :: 20 mg/L

REFERENCE :: EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 10(Suppl 10),1,1987 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X8936 No. of Facilities: 96 (estimated) No. of Industries: 2 No. of Occupations: 5 No. of Employees: 17827 (estimated) No. of Female Employees: 16443 (estimated)

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Symbol	GHS06, GHS08, GHS09
Signal Word	Danger
Hazard Statements	H300 + H310 + H330-H373-H411
Precautionary Statements	P260-P264-P273-P280-P284-P301 + P310
Personal Protective Equipment	Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes	T+:Verytoxic;N:Dangerous for the environment;
Risk Phrases	R26/27/28;R33;R51/53
Safety Phrases	S28-S36/37-S45-S61-S28A
RIDADR	UN 2237 6.1/PG 3
WGK Germany	2
RTECS	BX1575000
Packaging Group	III
Hazard Class	6.1
HS Code	29214210

This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.

This table lists upstream starting materials and downstream derivative products related to this chemical.

Precursor 10
CAS#:106-47-8 4-Chloroaniline CAS#:121-73-3 3-Nitrochlorobenzene CAS#:88-74-4 2-Nitroaniline CAS#:1516-58-1 Benzene,1-azido...
CAS#:881-51-6 N-(4-Chloro-2-n... CAS#:59320-13-7 4-Chloro-N-(2-h... CAS#:124-63-0 Methanesulfonyl... CAS#:539-03-7 4-Chloroacetanilide
CAS#:89-61-2 1,4-Dichloro-2-... CAS#:89284-67-3 Benzene, 1-azid...
DownStream 10
CAS#:5423-53-0 3-chloro-7,9,10... CAS#:5106-98-9 4-Chlorosalicyl... CAS#:34662-32-3 4-Chloro-2-nitr... CAS#:33468-35-8 6-Chloro-L-tryp...
CAS#:5470-75-7 6-Chloro-8-quin... CAS#:39060-31-6 3-chloro-9-oxid... CAS#:5388-62-5 4-Chloro-2,6-di... CAS#:480439-09-6 5-(4-chloro-2-n...
CAS#:41513-04-6 1-Bromo-4-chlor... CAS#:5448-43-1 6-CHLOROQUINOXALINE

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code	2921420090
Summary	HS:2921420090 aniline derivatives and their salts VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

This table lists relevant public references with title, journal and publication metadata for this compound.

[Toxicity of 4-chloro-2-nitroaniline and 2-chloro-4-nitroaniline to isolated rat hepatocytes].

Med. Lav. 82(3) , 253-60, (1991)

The toxicity of 4-chloro-2-nitroaniline (4C2NA) and 2-chloro-4-nitroaniline (2C4NA) was investigated on isolated rat hepatocytes following 1-3 hours of exposure to 0.2 and/or 2 mM of these xenobiotics...

Disposition and metabolism of 4-chloro-2-nitroaniline in the male F344 rat.

J. Toxicol. Environ. Health A 12(2-3) , 267-82, (1983)

The disposition and metabolism of 14C-labeled 4-chloro-2-nitroaniline (CNA) was studied in male F344 rats following oral or intravenous (iv) administration. The gastrointestinal absorption of CNA was ...

This table contains target information, in‑vitro & in‑vivo assay data for this compound.

Name: Cytochrome P450 Family 1 Subfamily A Member 2 (CYP1A2) small molecule antagonists: lu...
Source: 824
External Id: CYP273

Name: p53 small molecule agonists, cell-based qHTS assay: qHTS cell viability counter scree...
Source: 824
Target: N/A
External Id: P53600

Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes: qHTS ce...
Source: 824
Target: N/A
External Id: P53MS958

Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes: Summary
Source: 824
External Id: P53MS482

Name: p53 small molecule agonists, cell-based qHTS assay
Source: 824
External Id: P53344

Name: p53 small molecule agonists, cell-based qHTS assay with human liver microsomes
Source: 824
Target: tumor suppressor p53 [Homo sapiens]
External Id: P53MS233

Name: p53 small molecule agonists, cell-based qHTS assay with human liver microsomes: qHTS ...
Source: 824
Target: N/A
External Id: P53MS837

Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes
Source: 824
Target: tumor suppressor p53 [Homo sapiens]
External Id: P53MS898

Name: qHTS Assay for Small Molecule Inhibitors of the Human hERG Channel Activity
Source: NCGC
External Id: HERG01

Name: Adrenergic beta2 receptor (ADRB2) small molecule agonists, cell-based qHTS assay
Source: 824
External Id: ADRB2293

Total 215, Current Page 1 of 22

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

4-chloro-2-nitro-phenylamine

4-chloro-2-nitro-aniline

Red Salt Ciba VI

2-Nitro-4-chloroaniline

Benzenamine,4-chloro-2-nitro

Devol Red Salt F

Red Base Ciba VI

ZR DG BNW

EINECS 201-925-4

1-amino-2-nitro-4-chlorobenzene

MFCD00007836

Aniline,4-chloro-2-nitro

4-Chloro-2-nitroaniline

Red Salt Nbgl

4-Chloro-2-nitrobenzenamine

Devol Red F

Red Base Irga VI

azoamine red 2C

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the English name of 4-Chloro-2-nitroaniline?

A: The English name of 4-Chloro-2-nitroaniline is 4-Chloro-2-nitroaniline.

Q: What is the CAS number of 4-Chloro-2-nitroaniline?

A: CAS number of 4-Chloro-2-nitroaniline is 89-63-4.

Q: What is the safety information for 4-Chloro-2-nitroaniline?

A: Safety information for 4-Chloro-2-nitroaniline: S28-S36/37-S45-S61-S28A.

Q: What is the molecular formula of 4-Chloro-2-nitroaniline?

A: Molecular formula of 4-Chloro-2-nitroaniline is C6H5ClN2O2.

Q: What is the melting point of 4-Chloro-2-nitroaniline?

A: Melting point of 4-Chloro-2-nitroaniline is 117-119 °C(lit.).

Q: What is the boiling point of 4-Chloro-2-nitroaniline?

A: Boiling point of 4-Chloro-2-nitroaniline is 308.8±22.0 °C at 760 mmHg.

Q: What English synonyms does 4-Chloro-2-nitroaniline have?

A: English synonyms of 4-Chloro-2-nitroaniline: 4-chloro-2-nitro-phenylamine, 4-chloro-2-nitro-aniline, Red Salt Ciba VI, 2-Nitro-4-chloroaniline, Benzenamine,4-chloro-2-nitro, Devol Red Salt F, Red Base Ciba VI, ZR DG BNW, EINECS 201-925-4, 1-amino-2-nitro-4-chlorobenzene, MFCD00007836, Aniline,4-chloro-2-nitro, 4-Chloro-2-nitroaniline, Red Salt Nbgl, 4-Chloro-2-nitrobenzenamine, Devol Red F, Red Base Irga VI, azoamine red 2C.

Q: What are the upstream materials of 4-Chloro-2-nitroaniline?

A: Related upstream materials(CAS) of 4-Chloro-2-nitroaniline: 106-47-8;121-73-3;88-74-4;1516-58-1;881-51-6;59320-13-7;124-63-0;539-03-7;89-61-2;89284-67-3.

Q: How is the water solubility of 4-Chloro-2-nitroaniline?

A: Water solubility of 4-Chloro-2-nitroaniline: INSOLUBLE.

Q: What is the molecular weight of 4-Chloro-2-nitroaniline?

A: Molecular weight of 4-Chloro-2-nitroaniline is 172.569.

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd

Dayang Chem (Hangzhou) Co., Ltd.

Henan Tianfu Chemical Co., Ltd.

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 4-Chloro-2-nitroaniline
Price: Check
Purity: 99.7%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 4-Chloro-2-nitroaniline
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: 89-63-4 4-Chloro-2-nitroaniline
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Delivery: Inquiry
Contact: Anson
Email: info@tianfuchem.com

Get all suppliers and price by the below link:

4-Chloro-2-nitroaniline suppliers

4-Chloro-2-nitroaniline price

4-Chloro-2-nitroaniline

Names

Chemical & Physical Properties

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

Safety Information

Synthetic Route

Precursor & DownStream

Customs

Articles2

4-Chloro-2-nitroanilineBioassay

Synonyms

4-Chloro-2-nitroaniline | FAQ

4-Chloro-2-nitroanilinefactory

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.