Dutogliptin tartrate
Modify Date: 2024-02-04 11:26:16
Dutogliptin tartrate structure
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Common Name | Dutogliptin tartrate | ||
|---|---|---|---|---|
| CAS Number | 890402-81-0 | Molecular Weight | 391.18200 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C14H26BN3O9 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Dutogliptin tartrateDutogliptin tartrate (PHX-1149) is an orally available, potent, and selective dipeptidyl peptidase-4 (DPP4) inhibitor for the treatment of type 2 diabetes mellitus. |
| Name | (2R)-1-{2-[(3R)-pyrrolidin-3-ylamino]-acetyl}-pyrrolidine-2-boronic acid mono-L-tartrate salt |
|---|---|
| Synonym | More Synonyms |
| Description | Dutogliptin tartrate (PHX-1149) is an orally available, potent, and selective dipeptidyl peptidase-4 (DPP4) inhibitor for the treatment of type 2 diabetes mellitus. |
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| Related Catalog | |
| Target |
DPP4[1] |
| In Vivo | Dutogliptin exhibits low plasma protein binding (11%) and is rapidly absorbed with a Tmax of 3-4 h and a half-life of 10-13 h. Dutogliptin is metabolically stable and does not inhibit or induce the activity of major CYP450s[2]. |
| References |
| Molecular Formula | C14H26BN3O9 |
|---|---|
| Molecular Weight | 391.18200 |
| Exact Mass | 391.17600 |
| PSA | 199.89000 |
| L-tartrate salt of (2R)-1-{7-[(9R)-pyrrolidin-9-ylamino]-acetyl}-pyrrolidine-2-boronic acid |
| dutogliptin |