AZD 3988
Modify Date: 2025-08-25 08:30:41
AZD 3988 structure
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Common Name | AZD 3988 | ||
|---|---|---|---|---|
| CAS Number | 892489-52-0 | Molecular Weight | 456.44 | |
| Density | 1.402 | Boiling Point | N/A | |
| Molecular Formula | C23H22F2N4O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of AZD 3988AZD3988 is a diacylglycerol acyl transferase-1 (DGAT-1) inhibitor with IC50s of 6, 5, 11 nM for human, rat, mouse, respectively[1]. |
| Name | trans-4-[4-[[[5-[(3,4-Difluorophenyl)amino]-1,3,4-oxadiazol-2-yl]carbonyl]amino]phenyl]cyclohexaneacetic acid |
|---|---|
| Synonym | More Synonyms |
| Description | AZD3988 is a diacylglycerol acyl transferase-1 (DGAT-1) inhibitor with IC50s of 6, 5, 11 nM for human, rat, mouse, respectively[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 6 nM (h DGAT-1), 5 nM (Rat DGAT-1), 11 nM (Mouse DGAT-1)[1] |
| References |
| Density | 1.402 |
|---|---|
| Molecular Formula | C23H22F2N4O4 |
| Molecular Weight | 456.44 |
| Exact Mass | 456.16100 |
| PSA | 117.35000 |
| LogP | 5.23820 |
| Index of Refraction | 1.627 |
|
~80%
AZD 3988 CAS#:892489-52-0 |
| Literature: ASTRAZENECA AB; ASTRAZENECA UK LIMITED Patent: WO2007/144571 A1, 2007 ; Location in patent: Page/Page column 21-22 ; WO 2007/144571 A1 |
| 2H-Cyclopenta[b]furan-2-one,hexahydro-6-hydroxy |
| (trans-4-{4-[({5-[(3,4-difluorophenyl)amino]-1,3,4-oxadiazol-2-yl}carbonyl)amino]phenyl}cyclohexyl)acetic acid |
| 6-Hydroxyhexahydrocyclopenta[b]furan-2-one |
| (trans-2,3-Dihydroxy-cyclopentyl)-essigsaeure-lacton |