KX2-361

Modify Date: 2024-02-02 01:07:00

KX2-361 structure	Common Name	KX2-361
	CAS Number	897016-26-1	Molecular Weight	405.46
	Density	1.2±0.1 g/cm3	Boiling Point	660.1±55.0 °C at 760 mmHg
	Molecular Formula	C₂₄H₂₄FN₃O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	353.0±31.5 °C

Use of KX2-361

KX2-361 (KX-02) is a Src-kinase and tubulin polymerization inhibitor. KX2-361 shows good oral bioavailability and readily crosses the BBB in mice. KX2-361 shows anti-tumor activity and induces apoptosis of Glioblastoma (GBM) cell[1].

Name	RVW387BA9U
Synonym	More Synonyms

Description	KX2-361 (KX-02) is a Src-kinase and tubulin polymerization inhibitor. KX2-361 shows good oral bioavailability and readily crosses the BBB in mice. KX2-361 shows anti-tumor activity and induces apoptosis of Glioblastoma (GBM) cell[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Microtubule/Tubulin Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Src Signaling Pathways >> Cytoskeleton >> Microtubule/Tubulin
References	[1]. Ciesielski MJ, et al. KX2-361: a novel orally bioavailable small molecule dual Src/tubulin inhibitor that provides long term survival in a murine model of glioblastoma. J Neurooncol. 2018 Dec;140(3):519-527.

Density	1.2±0.1 g/cm3
Boiling Point	660.1±55.0 °C at 760 mmHg
Molecular Formula	C₂₄H₂₄FN₃O₂
Molecular Weight	405.46
Flash Point	353.0±31.5 °C
Exact Mass	405.185242
LogP	2.00
Vapour Pressure	0.0±2.0 mmHg at 25°C
Index of Refraction	1.598

N-(3-Fluorobenzyl)-2-{5-[4-(4-morpholinyl)phenyl]-2-pyridinyl}acetamide

RVW387BA9U

2-Pyridineacetamide, N-[(3-fluorophenyl)methyl]-5-[4-(4-morpholinyl)phenyl]-

DC Chemicals Limited
China
Product Name: KX2-361
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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