Cytochrome C

Modify Date: 2025-08-22 20:42:52

Cytochrome C Structure
Cytochrome C structure
 Common Name Cytochrome C
CAS Number 9007-43-6 Molecular Weight 884.887
Density N/A Boiling Point 1323.5ºC at 760 mmHg
Molecular Formula C42H52FeN8O6S2 Melting Point 300ºC
MSDS Chinese USA Flash Point 754.2ºC

 Use of Cytochrome C


Cytochrome C is a multi-functional enzyme involving in life and death decisions of the cell. Cytochrome C is essential in mitochondrial electron transport and intrinsic type II apoptosis[1].

 Names

Name Cytochrome C
Synonym More Synonyms

 Cytochrome C Biological Activity

Description Cytochrome C is a multi-functional enzyme involving in life and death decisions of the cell. Cytochrome C is essential in mitochondrial electron transport and intrinsic type II apoptosis[1].
Related Catalog
In Vitro 哺乳动物 Cytochrome C 在健康状态下清除活性氧 (ROS)，在凋亡过程中与辅因子 p66Shc 产生 ROS，氧化心磷脂[1]。
References

[1]. Hüttemann M, et al. The multiple functions of cytochrome c and their regulation in life and death decisions of the mammalian cell: From respiration to apoptosis. Mitochondrion. 2011 May;11(3):369-81.  

 Chemical & Physical Properties

Boiling Point 1323.5ºC at 760 mmHg
Melting Point 300ºC
Molecular Formula C42H52FeN8O6S2
Molecular Weight 884.887
Flash Point 754.2ºC
Exact Mass 884.280090
PSA 286.03000
LogP 3.85300
InChIKey WFVBWSTZNVJEAY-UHFFFAOYSA-L
SMILES CNC(=O)C(N)CSC(C)C1=C(C)c2cc3[n-]c(cc4[n-]c(cc5nc(cc1n2)C(C)=C5C(C)SCC(N)C(=O)NC)c(C)c4CCC(=O)O)c(CCC(=O)O)c3C.[Fe+2]
Storage condition −20°C
Water Solubility H2O: 10 mg/mL, clear, dark red-brown | 100 g/L (20 ºC)

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
HA5365000
CHEMICAL NAME :
Cytochrome C
CAS REGISTRY NUMBER :
9007-43-6
LAST UPDATED :
199701

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
10 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
6250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>3 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
250 mg/kg
SEX/DURATION :
female 1-22 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
20 ug/plate
REFERENCE :
ABCHA6 Agricultural and Biological Chemistry. (Maruzen Co. Ltd., POB 5050, Tokyo International, Tokyo 100-31, Japan) V.25- 1961- Volume(issue)/page/year: 45,327,1981

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi: Irritant;Xn: Harmful;
Risk Phrases 36/37/38-20/21/22
Safety Phrases S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS HA5365000
HS Code 3507909000

 Customs

HS Code 3507909000

 Articles109

More Articles
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Involvement of CaM-CaMKII-ERK in bisphenol A-induced Sertoli cell apoptosis.

Toxicology 324 , 27-34, (2014)

Bisphenol A (BPA), one of the most prevalent chemicals for daily use, has been reported as a xenoestrogen to induce reproductive toxicity, but its mechanism is poorly understood. In the present study,...

Assessment of cytochrome C oxidase dysfunction in the substantia nigra/ventral tegmental area in schizophrenia.

PLoS ONE 9(6) , e100054, (2014)

Perturbations in metabolism are a well-documented but complex facet of schizophrenia pathology. Optimal cellular performance requires the proper functioning of the electron transport chain, which is c...

 Synonyms

Cytochromert
EINECS 232-700-9
myohematin
Cytor-est
21H,23H-Porphine-2,18-dipropanoic acid, 7,12-bis[1-[[2-amino-3-(methylamino)-3-oxopropyl]thio]ethyl]-3,8,13,17-tetramethyl-, iron(2+) salt (1:1)
CYT-C
Iron(2+) (1Z,6Z,12Z,17Z)-4,9-bis(1-{[2-amino-3-(methylamino)-3-oxopropyl]sulfanyl}ethyl)-15,19-bis(2-carboxyethyl)-5,10,14,20-tetramethyl-21,22,23,24-tetraazapentacyclo[16.2.1.1.1.1] tetracosa-1,3(24),4,6,8,10,12,14,16(22),17,19-undecaene-21,23-diide
Cytomac P
cytorest
MFCD00130890
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