Urokinase structure
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Common Name | Urokinase | ||
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CAS Number | 9039-53-6 | Molecular Weight | N/A | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C21H25BrN2O3 | Melting Point | N/A | |
MSDS | USA | Flash Point | N/A |
Use of UrokinaseUrokinase peptidolytic (Urokinase-type plasminogen activator) is a serine protease, an inactive form (zymogen) of the serine protease plasminogen. Activation of plasmin triggers a proteolytic cascade reaction, which in turn participates in thrombolysis or extracellular matrix degradation, implicated in vascular disease and cancer-related research[1]. |
Name | Urokinase |
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Synonym | More Synonyms |
Description | Urokinase peptidolytic (Urokinase-type plasminogen activator) is a serine protease, an inactive form (zymogen) of the serine protease plasminogen. Activation of plasmin triggers a proteolytic cascade reaction, which in turn participates in thrombolysis or extracellular matrix degradation, implicated in vascular disease and cancer-related research[1]. |
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Related Catalog | |
In Vitro | Urokinase peptidolytic(uPA) 在非小细胞肺癌 (NSCLC) 中能够增加 uPAR 蛋白质和 mRNA 水平的表达[1]。 |
References |
Molecular Formula | C21H25BrN2O3 |
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Appearance of Characters | powder | white |
Storage condition | 2-8°C |
Water Solubility | Soluble in water. | Reconstitute in water at 100µg/ml |
Hazard Codes | B |
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RIDADR | NONH for all modes of transport |
WGK Germany | 3 |
RTECS | OB8900000 |
Hepatic stellate cells orchestrate clearance of necrotic cells in a hypoxia-inducible factor-1α-dependent manner by modulating macrophage phenotype in mice.
J. Immunol. 192(8) , 3847-57, (2014) Hypoxia-inducible factor-1α (HIF-1α) is activated in hepatic stellate cells (HSCs) by hypoxia and regulates genes important for tissue repair. Whether HIF-1α is activated in HSCs after acute injury an... |
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Tissue-type plasminogen activator deficiency delays bone repair: roles of osteoblastic proliferation and vascular endothelial growth factor.
Am. J. Physiol. Endocrinol. Metab. 307(3) , E278-88, (2014) Further development in research of bone regeneration is necessary to meet the clinical demand for bone reconstruction. Recently, we reported that plasminogen is crucial for bone repair through enhance... |
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Endocrine regulation of airway contractility is overlooked.
J. Endocrinol. 222(2) , R61-73, (2014) Asthma is a prevalent respiratory disorder triggered by a variety of inhaled environmental factors, such as allergens, viruses, and pollutants. Asthma is characterized by an elevated activation of the... |
urokinase, high mw (urine) |
ec 3.4.99.26 |
urokinase, low mw (urine) |
urokinase |
urokinase upa 2-chain |
urokinase, high molecular weight |
urokinase 2-chain |
MFCD00132566 |
urokinase (mixed) |