m-PEG16-NH2

Modify Date: 2024-01-12 09:17:36

m-PEG16-NH2 Structure
m-PEG16-NH2 structure
Common Name m-PEG16-NH2
CAS Number 907577-50-8 Molecular Weight 735.89800
Density N/A Boiling Point N/A
Molecular Formula C33H69NO16 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of m-PEG16-NH2


m-PEG16-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name MeO-16eg-NH2
Synonym More Synonyms

 m-PEG16-NH2 Biological Activity

Description m-PEG16-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Molecular Formula C33H69NO16
Molecular Weight 735.89800
Exact Mass 735.46200
PSA 173.70000
LogP 0.54080

 Synonyms

mPEG16-NH2