Lu AA47070
Modify Date: 2024-01-09 19:15:40
Lu AA47070 structure
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Common Name | Lu AA47070 | ||
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| CAS Number | 913842-25-8 | Molecular Weight | 463.39 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C17H20F2N3O6PS | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Lu AA47070Lu AA47070 is a phosphonooxymethylene prodrug of a potent and selective Adenosine A2A receptor antagonist. Lu AA47070 reverses the motor and motivational effects produced by dopamine D2 receptor blockade[1][2]. |
| Name | Lu AA47070 |
|---|---|
| Synonym | More Synonyms |
| Description | Lu AA47070 is a phosphonooxymethylene prodrug of a potent and selective Adenosine A2A receptor antagonist. Lu AA47070 reverses the motor and motivational effects produced by dopamine D2 receptor blockade[1][2]. |
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| Related Catalog | |
| In Vivo | Lu AA47070 (3.75、7.5、15、30 mg/kg；腹腔注射) 逆转由亚慢性给药 D2 拮抗剂匹莫齐特（1.0 mg/kg；腹腔注射）引起的下颌颤动、僵直和运动抑制[2]< /sup>。 Animal Model: Male Sprague Dawley rats[2] Dosage: 3.75, 7.5, 15, 30 mg/kg Administration: I.p. Result: Reversed the tremulous jaw movements, catalepsy, and locomotor suppression induced by subchronic administration of the D2 antagonist pimozide (1.0 mg/kg IP). |
| References |
| Molecular Formula | C17H20F2N3O6PS |
|---|---|
| Molecular Weight | 463.39 |
| Exact Mass | 463.07800 |
| PSA | 168.27000 |
| LogP | 3.08340 |
| phosphoric acid mono{2-[(E/Z)-4-(3,3-dimethylbutyrylamino)-3,5-difluorobenzoylimino]thiazol-3-ylmethyl} ester |
| phosphoric acid mono-{2-[(E/Z)-4-(3,3-dimethyl-butyrylamino)-3,5-difluoro-benzoylimino]-thiazol-3-ylmethyl} ester |
| LU-AA47070 |