Benzyl-PEG2-acid

Modify Date: 2024-01-08 23:43:54

Benzyl-PEG2-acid Structure
Benzyl-PEG2-acid structure
Common Name Benzyl-PEG2-acid
CAS Number 91555-65-6 Molecular Weight 224.25
Density N/A Boiling Point N/A
Molecular Formula C12H16O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Benzyl-PEG2-acid


Benzyl-PEG2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Benzyl-PEG2-acid
Synonym More Synonyms

 Benzyl-PEG2-acid Biological Activity

Description Benzyl-PEG2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C12H16O4
Molecular Weight 224.25

 Safety Information

Hazard Codes Xn

 Synonyms

MFCD28096691