YS121
Modify Date: 2024-01-05 10:20:54
YS121 structure
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Common Name | YS121 | ||
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| CAS Number | 916482-17-2 | Molecular Weight | 407.957 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 557.4±50.0 °C at 760 mmHg | |
| Molecular Formula | C20H26ClN3O2S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 290.9±30.1 °C | |
Use of YS121YS121 is a dual inhibitor of microsomal prostaglandin E2 synthase-1 (mPGES-1; IC50=3.4 μM) and 5-lipoxygenase (5-LOX; IC50=6.5 μM). YS121 dose- dependently reduces PGE2 production with EC50=12 μM in IL-1β-stimulated A549 cells[1]. |
| Name | 2-[4-chloro-6-(2,3-dimethylanilino)pyrimidin-2-yl]sulfanyloctanoic acid |
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| Synonym | More Synonyms |
| Description | YS121 is a dual inhibitor of microsomal prostaglandin E2 synthase-1 (mPGES-1; IC50=3.4 μM) and 5-lipoxygenase (5-LOX; IC50=6.5 μM). YS121 dose- dependently reduces PGE2 production with EC50=12 μM in IL-1β-stimulated A549 cells[1]. |
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| Related Catalog | |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 557.4±50.0 °C at 760 mmHg |
| Molecular Formula | C20H26ClN3O2S |
| Molecular Weight | 407.957 |
| Flash Point | 290.9±30.1 °C |
| Exact Mass | 407.143433 |
| PSA | 100.41000 |
| LogP | 7.93 |
| Vapour Pressure | 0.0±1.6 mmHg at 25°C |
| Index of Refraction | 1.601 |
| Octanoic acid, 2-[[4-chloro-6-[(2,3-dimethylphenyl)amino]-2-pyrimidinyl]thio]- |
| YS121 |
| Pirinixic acid-based compound,6a |
| 2-({4-Chloro-6-[(2,3-dimethylphenyl)amino]-2-pyrimidinyl}sulfanyl)octanoic acid |