D-Cysteine

Modify Date: 2024-01-02 10:30:17

D-Cysteine Structure
D-Cysteine structure
Common Name D-Cysteine
CAS Number 921-01-7 Molecular Weight 121.158
Density 1.3±0.1 g/cm3 Boiling Point 293.9±35.0 °C at 760 mmHg
Molecular Formula C3H7NO2S Melting Point 230ºC
MSDS Chinese USA Flash Point 131.5±25.9 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of D-Cysteine


D-Cysteine is the D-isomer of cysteine and a powerful inhibitor of Escherichia coli growth. D-cysteine is mediated by D-amino acid oxidase to produce H2S and is a neuroprotectant against cerebellar ataxias. D-Cysteine could inhibit the growth and cariogenic virulence of dual-species biofilms formed by S. mutans and S. sanguinis[1][2][3].

 Names

Name D-cysteine
Synonym More Synonyms

 D-Cysteine Biological Activity

Description D-Cysteine is the D-isomer of cysteine and a powerful inhibitor of Escherichia coli growth. D-cysteine is mediated by D-amino acid oxidase to produce H2S and is a neuroprotectant against cerebellar ataxias. D-Cysteine could inhibit the growth and cariogenic virulence of dual-species biofilms formed by S. mutans and S. sanguinis[1][2][3].
Related Catalog
Target

Human Endogenous Metabolite

References

[1]. Seki T. Availability of D-cysteine as a protectant for cerebellar neurons. Nihon Yakurigaku Zasshi. 2019;154(3):133-137.

[2]. Soutourina J, et al. Role of D-cysteine desulfhydrase in the adaptation of Escherichia coli to D-cysteine. J Biol Chem. 2001 Nov 2;276(44):40864-72.

[3]. Guo X1, et al. Effect of D-cysteine on dual-species biofilms of Streptococcus mutans and Streptococcus sanguinis. Sci Rep. 2019 Apr 30;9(1):6689.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 293.9±35.0 °C at 760 mmHg
Melting Point 230ºC
Molecular Formula C3H7NO2S
Molecular Weight 121.158
Flash Point 131.5±25.9 °C
Exact Mass 121.019745
PSA 102.12000
LogP 0.23
Vapour Pressure 0.0±1.3 mmHg at 25°C
Index of Refraction 1.550
Storage condition −20°C
Stability Stable. Incompatible with strong oxidizing agents.

 MSDS

Material Safety Data Sheet

Section1. Identification of the substance
Product Name: D-Cysteine
Synonyms:

Section2. Hazards identification
Harmful by inhalation, in contact with skin, and if swallowed.
H302:Harmful if swallowed
P264:Wash thoroughly after handling
P270:Do not eat, drink or smoke when using this product
P301+P312:IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell
P330:Rinse mouth

Section3. Composition/information on ingredients.
Ingredient name:D-Cysteine
CAS number:921-01-7

Section4. First aid measures
Skin contact:Immediately wash skin with copious amounts of water for at least 15 minutes while removing
contaminated clothing and shoes. If irritation persists, seek medical attention.
Eye contact:Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate
flushing of the eyes by separating the eyelids with fingers. If irritation persists, seek medical
attention.
Inhalation:Remove to fresh air. In severe cases or if symptoms persist, seek medical attention.
Ingestion:Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention.

Section5. Fire fighting measures
In the event of a fire involving this material, alone or in combination with other materials, use dry
powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus
should be worn.

Section6. Accidental release measures
Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national
standards.
Respiratory precaution:Wear approved mask/respirator
Hand precaution:Wear suitable gloves/gauntlets
Skin protection:Wear suitable protective clothing
Eye protection:Wear suitable eye protection
Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container
for disposal. See section 12.
Environmental precautions: Do not allow material to enter drains or water courses.

Section7. Handling and storage
This product should be handled only by, or under the close supervision of, those properly qualified
Handling:
in the handling and use of potentially hazardous chemicals, who should take into account the fire,
health and chemical hazard data given on this sheet.
Storage:Store in closed vessels, refrigerated.

Section8. Exposure Controls / Personal protection
Engineering Controls: Use only in a chemical fume hood.
Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles.
General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse.

Section9. Physical and chemical properties
Appearance:Not specified
Boiling point:No data
Melting point:No data
Flash point:No data
Density:No data
Molecular formula: C3H7NO2S
Molecular weight: 121.2

Section10. Stability and reactivity
Conditions to avoid: Heat, flames and sparks.
Materials to avoid: Oxidizing agents.
Possible hazardous combustion products: Carbon monoxide, nitrogen oxides, sulfur oxides.

Section11. Toxicological information
No data.

Section12. Ecological information
No data.

Section13. Disposal consideration
Arrange disposal as special waste, by licensed disposal company, in consultation with local waste
disposal authority, in accordance with national and regional regulations.

Section14. Transportation information
Non-harzardous for air and ground transportation.

Section15. Regulatory information
No chemicals in this material are subject to the reporting requirements of SARA Title III, Section
302, or have known CAS numbers that exceed the threshold reporting levels established by SARA
Title III, Section 313.


SECTION 16 - ADDITIONAL INFORMATION
N/A

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases 26-36/37/39
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 29309013

 Synthetic Route

 Customs

HS Code 29309013

 Articles17

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 Synonyms

(2S)-2-amino-3-mercaptopropanoic acid
S-cysteine
(D,L)-H-Cys-OH
D-Cystein
MFCD00066461
D-Amino-3-mercaptopropionic acid
(S)-2-amino-3-mercaptopropanoic acid
(2S)-2-amino-3-sulfanylpropanoic acid
EINECS 213-062-0
(S)-2-Amino-3-mercaptopropionic acid
Cysteine,D
2-amino-3-sulfopropionic acid
D-Zystein
Cysteine, D-
H-D-Cys-OH
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