BENOXATHIAN HCL

Modify Date: 2024-04-13 23:05:12

BENOXATHIAN HCL Structure
BENOXATHIAN HCL structure
Common Name BENOXATHIAN HCL
CAS Number 92642-97-2 Molecular Weight 397.91600
Density N/A Boiling Point 500.7ºC at 760 mmHg
Molecular Formula C19H24ClNO4S Melting Point N/A
MSDS Chinese USA Flash Point 256.6ºC

 Use of BENOXATHIAN HCL


Benoxathian hydrochloride is a potent α1 adrenoceptor antagonist, can be used for researching anorexia[1].

 Names

Name N-(2,3-dihydro-1,4-benzoxathiin-2-ylmethyl)-2-(2,6-dimethoxyphenoxy)ethanamine,hydrochloride
Synonym More Synonyms

 BENOXATHIAN HCL Biological Activity

Description Benoxathian hydrochloride is a potent α1 adrenoceptor antagonist, can be used for researching anorexia[1].
Related Catalog
Target

α1 Adrenoceptor[1]

In Vivo Benoxathian hydrochloride (10 nM; paraventricular nucleus injection) completely reverses the anorexia induced by 2.5, 5.0 or 10.0 mg/kg Phenylpropanolamine (IP) in rats[1].
References

[1]. Wellman PJ, et al. Reversal of phenylpropanolamine anorexia in rats by the alpha-1 receptor antagonist benoxathian. Pharmacol Biochem Behav. 1991 Apr;38(4):905-8.

 Chemical & Physical Properties

Boiling Point 500.7ºC at 760 mmHg
Molecular Formula C19H24ClNO4S
Molecular Weight 397.91600
Flash Point 256.6ºC
Exact Mass 397.11100
PSA 74.25000
LogP 4.41840

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
WGK Germany 3

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 Synonyms

2-[[[2-(2,6-Dimethoxyphenoxy)ethyl]-amino]-methyl]-1,4-benzoxathian hydrochloride
Benoxathian hydrochloride
Benoxathian HCl