TFC 007
Modify Date: 2024-01-19 20:23:55
TFC 007 structure
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Common Name | TFC 007 | ||
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| CAS Number | 927878-49-7 | Molecular Weight | 487.55 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C27H29N5O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of TFC 007TFC-007, a selective hematopoietic prostaglandin D synthase (H-PGDS) inhibitor, show high inhibitory activity against H-PGDS enzyme (IC50 value of 83 nM). TFC-007 can be used for composing H-PGDS degradation inducer PROTAC(H-PGDS)-1 (TFC-007 binds to H-PGDS, and Pomalidomide binds to cereblon)[1]. |
| Name | TFC 007 |
|---|---|
| Synonym | More Synonyms |
| Description | TFC-007, a selective hematopoietic prostaglandin D synthase (H-PGDS) inhibitor, show high inhibitory activity against H-PGDS enzyme (IC50 value of 83 nM). TFC-007 can be used for composing H-PGDS degradation inducer PROTAC(H-PGDS)-1 (TFC-007 binds to H-PGDS, and Pomalidomide binds to cereblon)[1]. |
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| Related Catalog | |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Molecular Formula | C27H29N5O4 |
| Molecular Weight | 487.55 |
| Exact Mass | 487.221954 |
| LogP | 1.82 |
| Index of Refraction | 1.639 |
| 5-Pyrimidinecarboxamide, N-[4-[4-(4-morpholinylcarbonyl)-1-piperidinyl]phenyl]-2-phenoxy- |
| N-{4-[4-(4-Morpholinylcarbonyl)-1-piperidinyl]phenyl}-2-phenoxy-5-pyrimidinecarboxamide |
| N-[4-[4-(4-Morpholinylcarbonyl)-1-piperidinyl]phenyl]-2-phenoxy-5-pyrimidinecarboxamide |