Neurodazine
Modify Date: 2024-01-02 22:20:55
Neurodazine structure
|
Common Name | Neurodazine | ||
|---|---|---|---|---|
| CAS Number | 937807-66-4 | Molecular Weight | 460.952 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 669.0±55.0 °C at 760 mmHg | |
| Molecular Formula | C27H21ClN2O3 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 358.4±31.5 °C | |
| Symbol |
GHS05, GHS06 |
Signal Word | Danger | |
Use of NeurodazineNeurodazine is an imidazole-based small molecule, serve as a promoter of neurogenesisin pluripotent cells. Neurodazine promotes neurogenesis by activating Wnt and Shh signaling pathways. Neurodazine selectively suppresses astrocyte differentiation of P19 cells[1][2]. |
| Name | 2-[5-(3-chlorophenyl)furan-2-yl]-4,5-bis(4-methoxyphenyl)-1H-imidazole |
|---|---|
| Synonym | More Synonyms |
| Description | Neurodazine is an imidazole-based small molecule, serve as a promoter of neurogenesisin pluripotent cells. Neurodazine promotes neurogenesis by activating Wnt and Shh signaling pathways. Neurodazine selectively suppresses astrocyte differentiation of P19 cells[1][2]. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 669.0±55.0 °C at 760 mmHg |
| Molecular Formula | C27H21ClN2O3 |
| Molecular Weight | 460.952 |
| Flash Point | 358.4±31.5 °C |
| Exact Mass | 460.155365 |
| PSA | 56.37000 |
| LogP | 6.42 |
| Vapour Pressure | 0.0±2.0 mmHg at 25°C |
| Index of Refraction | 1.613 |
| Symbol |
GHS05, GHS06 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H301-H318-H413 |
| Precautionary Statements | P280-P301 + P310-P305 + P351 + P338 |
| Personal Protective Equipment | Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges |
| RIDADR | UN 2811 6.1 / PGIII |
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Front. Endocrinol. (Lausanne.) 2 , 117, (2011) The proliferative pool and regenerative potential of neural stem cells diminishes with age, a phenomenon that may be exacerbated in prodromal and mild Alzheimer's disease (AD) brains. In parallel, the... |
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Role of ciliary neurotrophic factor in the proliferation and differentiation of neural stem cells.
J. Alzheimers Dis. 37(3) , 587-92, (2013) Ciliary neurotrophic factor (CNTF) is a pleiotropic cytokine that has been fully studied for its structure, receptor, and signaling pathways and its multiplex effects on neural system, skeletal muscle... |
| 1H-Imidazole, 2-[5-(3-chlorophenyl)tetrahydro-2-furanyl]-4,5-bis(4-methoxyphenyl)- |
| Neurodazine |
| 2-[5-(3-Chlorophenyl)tetrahydro-2-furanyl]-4,5-bis(4-methoxyphenyl)-1H-imidazole |