2-Ethoxybenzamide

Modify Date: 2024-01-18 18:18:59

2-Ethoxybenzamide Structure
2-Ethoxybenzamide structure
Common Name 2-Ethoxybenzamide
CAS Number 938-73-8 Molecular Weight 165.189
Density 1.1±0.1 g/cm3 Boiling Point 302.0±25.0 °C at 760 mmHg
Molecular Formula C9H11NO2 Melting Point 129-134 °C
MSDS USA Flash Point 153.7±19.5 °C

 Use of 2-Ethoxybenzamide


2-Ethoxybenzamide is widely used as an antipyretic anodyne.

 Names

Name 2-Ethoxybenzamide
Synonym More Synonyms

 2-Ethoxybenzamide Biological Activity

Description 2-Ethoxybenzamide is widely used as an antipyretic anodyne.
Related Catalog

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 302.0±25.0 °C at 760 mmHg
Melting Point 129-134 °C
Molecular Formula C9H11NO2
Molecular Weight 165.189
Flash Point 153.7±19.5 °C
Exact Mass 165.078979
PSA 52.32000
LogP 1.40
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.538
Water Solubility <0.1 g/100 mL at 16 ºC

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CV4900000
CHEMICAL NAME :
Benzamide, o-ethoxy-
CAS REGISTRY NUMBER :
938-73-8
BEILSTEIN REFERENCE NO. :
2208582
LAST UPDATED :
199701
DATA ITEMS CITED :
10
MOLECULAR FORMULA :
C9-H11-N-O2
MOLECULAR WEIGHT :
165.21
WISWESSER LINE NOTATION :
ZVR BO2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2630 mg/kg
TOXIC EFFECTS :
Behavioral - sleep Lungs, Thorax, or Respiration - dyspnea
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
700 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
400 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
1500 mg/kg
TOXIC EFFECTS :
Behavioral - sleep Cardiac - other changes Lungs, Thorax, or Respiration - dyspnea
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
544 gm/kg/54W-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors
TYPE OF TEST :
Morphological transformation

MUTATION DATA

TYPE OF TEST :
Cytogenetic analysis
TEST SYSTEM :
Rodent - hamster Fibroblast
DOSE/DURATION :
500 mg/L
REFERENCE :
ESKHA5 Eisei Shikenjo Hokoku. Bulletin of the Institute of Hygienic Sciences. (Kokuritsu Eisei Shikenjo Kagaku, 18-1 Bushitsu Johobu, Setagaya-ku, Tokyo 158, Japan) V.1- 1886- Volume(issue)/page/year: (96),55,1978

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases S24/25
RIDADR NONH for all modes of transport
RTECS CU4381000
HS Code 29242995

 Synthetic Route

~96%

2-Ethoxybenzamide Structure

2-Ethoxybenzamide

CAS#:938-73-8

Literature: Skvortsova, G. G.; Andriyankova, L. V.; Stepanova, Z. V. Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1983 , vol. 32, # 10 p. 2153 - 2155 Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1983 , # 10 p. 2389 - 2391

~72%

2-Ethoxybenzamide Structure

2-Ethoxybenzamide

CAS#:938-73-8

Literature: Ali, Md. Ashif; Punniyamurthy, Tharmalingam Advanced Synthesis and Catalysis, 2010 , vol. 352, # 2-3 p. 288 - 292

~%

2-Ethoxybenzamide Structure

2-Ethoxybenzamide

CAS#:938-73-8

Literature: Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), , vol. 32, # 10 p. 2153 - 2155 Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, , # 10 p. 2389 - 2391

~%

2-Ethoxybenzamide Structure

2-Ethoxybenzamide

CAS#:938-73-8

Literature: Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), , vol. 32, # 10 p. 2153 - 2155 Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, , # 10 p. 2389 - 2391

~%

2-Ethoxybenzamide Structure

2-Ethoxybenzamide

CAS#:938-73-8

Literature: Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), , vol. 32, # 10 p. 2153 - 2155 Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, , # 10 p. 2389 - 2391

~19%

2-Ethoxybenzamide Structure

2-Ethoxybenzamide

CAS#:938-73-8

Literature: Skvortsova, G. G.; Andriyankova, L. V.; Stepanova, Z. V. Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1983 , vol. 32, # 10 p. 2153 - 2155 Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1983 , # 10 p. 2389 - 2391

~%

2-Ethoxybenzamide Structure

2-Ethoxybenzamide

CAS#:938-73-8

Literature: Justus Liebigs Annalen der Chemie, , vol. 98, p. 258

~%

2-Ethoxybenzamide Structure

2-Ethoxybenzamide

CAS#:938-73-8

Literature: Monatshefte fuer Chemie, , vol. 12, p. 396

~%

2-Ethoxybenzamide Structure

2-Ethoxybenzamide

CAS#:938-73-8

Literature: Acad. romine Stud. Cerc. Chim.Chem.Abstr., , vol. 2, p. 199 Acad. romine Stud. Cerc. Chim.Chem.Abstr., , p. 9382

 Customs

HS Code 2924299090
Summary 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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 Synonyms

2-Ethoxyphenylformamide
2-ethoxy-benzoic acid amide
Etamide
Ethosalicyl
Aethylaethersalicylsaeure-amid
Benzamide,2-ethoxy
2-Aethoxy-benzamid
EINECS 213-346-4
4-10-00-00175 (Beilstein Handbook Reference)
Pirosolvina
Ethenzamide
2-Ethoxybenzenecarbonamide
MFCD00007977
Phenetolcarbamide
Salicylamide o-Ethyl Ether
Benzamide, 2-ethoxy-
Etenzamide [DCIT]
2-Aethoxy-benzoesaeure-amid
Ethenzamide (JP15)
2-Ethoxybenzamide
o-Ethoxybenzamide
Etenzamide
Ethbenzamide
2-Ethoxybenzolcarboxamid
O-Aethyl-salicylamid
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