α-Amylase-IN-3

Modify Date: 2024-04-05 21:04:26

α-Amylase-IN-3 Structure
α-Amylase-IN-3 structure
Common Name α-Amylase-IN-3
CAS Number 93944-58-2 Molecular Weight 267.24
Density N/A Boiling Point N/A
Molecular Formula C15H9NO4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of α-Amylase-IN-3


α-Amylase-IN-3 (Compound 4) is a none-competitive type of α-Amylase inhibitor with an IC50 value of 18.04 μM, which also has radical scavenging activities (DPPH and ABTS) with IC50 values of 16.04 μM (DPPH) and 16.99 μM (ABTS), respectively. α-Amylase-IN-3 has good protein–ligand interactions profile against α-Amylase. α-Amylase-IN-3 may have pharmacological activities such as anti-oxidative, anti-inflammatory inhibitory, which is helpful for the development of diabetes and oxidative stress associated disease[1].

 Names

Name α-Amylase-IN-3

 α-Amylase-IN-3 Biological Activity

Description α-Amylase-IN-3 (Compound 4) is a none-competitive type of α-Amylase inhibitor with an IC50 value of 18.04 μM, which also has radical scavenging activities (DPPH and ABTS) with IC50 values of 16.04 μM (DPPH) and 16.99 μM (ABTS), respectively. α-Amylase-IN-3 has good protein–ligand interactions profile against α-Amylase. α-Amylase-IN-3 may have pharmacological activities such as anti-oxidative, anti-inflammatory inhibitory, which is helpful for the development of diabetes and oxidative stress associated disease[1].
Related Catalog
Target

IC50: 18.04 μM (α-Amylase), 16.04 μM (DPPH), 16.99 μM (ABTS)[1].

References

[1]. Na Li, et al. Design, synthesis and biological evaluation of novel plumbagin derivatives as potent antitumor agents with STAT3 inhibition. Bioorg Chem. 2020 Nov;104:104208.

 Chemical & Physical Properties

Molecular Formula C15H9NO4
Molecular Weight 267.24