p,p'-DDE-d8
Modify Date: 2024-01-16 12:30:07
p,p'-DDE-d8 structure
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Common Name | p,p'-DDE-d8 | ||
|---|---|---|---|---|
| CAS Number | 93952-19-3 | Molecular Weight | 326.07500 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C14Cl4D8 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of p,p'-DDE-d8p,p'-DDE-d8 is the deuterium labeled p,p'-DDE[1]. p,p'-DDE (4,4'-DDE), a major metabolite of persistent dichlorodiphenyltrichloroethane (DDT), is a potent androgen receptor antagonist, with an IC50 of 5 μM and a Ki of 3.5 μM[2]. |
| Name | 4,4'-dde d8 |
|---|
| Description | p,p'-DDE-d8 is the deuterium labeled p,p'-DDE[1]. p,p'-DDE (4,4'-DDE), a major metabolite of persistent dichlorodiphenyltrichloroethane (DDT), is a potent androgen receptor antagonist, with an IC50 of 5 μM and a Ki of 3.5 μM[2]. |
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| Related Catalog | |
| In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
| References |
| Molecular Formula | C14Cl4D8 |
|---|---|
| Molecular Weight | 326.07500 |
| Exact Mass | 323.98800 |
| LogP | 6.18790 |